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Chemical Transmission at the Insect Excitatory Neuromuscular Synapse

Nature volume 210, pages 634–636 (1966)Cite this article

Abstract

GLUTAMIC acid mimics the transmitter at the crustacean excitatory neuromuscular synapse1 and has been tentatively identified with the chemical mediator at the insect peripheral excitatory synapse2,3. Similarities in the pharmacology of insect and crustacean excitatory neuromuscular synapses are, perhaps, to be expected since the pharmacological properties of their peripheral inhibitory synapses are remarkably similar2,4. In an effort to determine the site of action of glutamic acid on the insect neuromuscular system we have examined the effects of this substance on the electrical and mechanical properties of a locust neuromuscular preparation.

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Authors and Affiliations

  1. Department of Zoology, University of Glasgow,

    P. N. R. USHERWOOD & P. MACHILI

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  1. P. N. R. USHERWOOD
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  2. P. MACHILI
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USHERWOOD, P., MACHILI, P. Chemical Transmission at the Insect Excitatory Neuromuscular Synapse. Nature 210, 634–636 (1966). https://doi.org/10.1038/210634a0

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