Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Testing Chemicals for Mutagenicity in a Mammal

Abstract

WHILE admitting that mammals would be preferable to diptera for testing newly introduced drugs for possible genetic (that is, mutagenic) effects, Prof. Lüning1 argues that tests with mice would be expensive and time consuming and therefore advocates the use of Drosophila larvae grown on medium containing the drug, which are then tested for chromosome loss and non-disjunction.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Lüning, K. G., Nature, 209, 84 (1966).

    Article  ADS  Google Scholar 

  2. Bateman, A. J., Heredity, 12, 213 (1958).

    Article  Google Scholar 

  3. Bateman, A. J., Heredity, 12, 467 (1958).

    Article  Google Scholar 

  4. Bateman, A. J., Genet. Res., 1, 381 (1960).

    Article  Google Scholar 

  5. Russell, W. L., Russell, L. B., and Kimball, A. W., Amer. Nat., 88, 269 (1954).

    Article  Google Scholar 

  6. Bateman, A. J., and Chandley, A. C., Nature, 193, 705 (1962).

    Article  ADS  CAS  Google Scholar 

  7. Partington, M., and Bateman, A. J., Heredity, 19, 191 (1964).

    Article  CAS  Google Scholar 

  8. Partington, M., and Jackson, H., Genet. Res., 4, 333 (1963).

    Article  Google Scholar 

  9. Bateman, A. J., in Ann. Rep. Brit. Emp. Cancer Camp. 1965 (in the press).

  10. Lyon, M. F., Phillips, R. J. S., and Searle, A. G., Z. Vererb., 93, 7 (1962).

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

BATEMAN, A. Testing Chemicals for Mutagenicity in a Mammal. Nature 210, 205–206 (1966). https://doi.org/10.1038/210205a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/210205a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing