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Rate of Cell Proliferation in a Mouse Squamous Cell Carcinoma

Abstract

TUMOURS apparently grow faster than normal tissues. It seems to be a widely accepted belief that this always depends on the rapid rate of cell proliferation in malignant tumours. Growth, however, may be defined as the net gain of renewal over loss. If the ‘rate of cell renewal’, the input, and the ‘rate of cell death’, the output, are two continuous functions, F(t)and G(t) respectively, then at a moment t the tumour mass (M) is:

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EVENSEN, A., HILMAR IVERSEN, O. Rate of Cell Proliferation in a Mouse Squamous Cell Carcinoma. Nature 196, 383–384 (1962). https://doi.org/10.1038/196383a0

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