Abstract
PART of the vitamin B12 activity in rat serum, as assayed with Lactobacillus leichmannii, is stable to alkali1,2, which destroys vitamin B12 and almost all the vitamin B12 activity in human serum3. In this communication we present observations showing that rat serum contains four separate components with vitamin B12 activity for Lactobacillus leichmannii.
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References
Spray, G. H., and Taylor, K. B., Nature, 182, 1309 (1958).
Booth, M. A., and Spray, G. H., Brit. J. Hæmat., 6, 288 (1960).
Spray, G. H., Clin. Sci., 14, 661 (1955).
Smith, E. L., and Cuthbertson, W. F. J., Biochem. J., 45, xii (1949).
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BOOTH, M., SPRAY, G. Vitamin B12 Activity in the Serum of the Rat. Nature 193, 74–75 (1962). https://doi.org/10.1038/193074a0
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DOI: https://doi.org/10.1038/193074a0
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