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Fibrosarcoma in a Rabbit following β-Irradiation of the Skin

Abstract

THIS communication describes the gross and histological appearance of a fibrosarcoma which occurred four years after exposing an area of rabbit skin to 16,000 rads from a phosphorus-32 plaque. The only previous observation of skin tumours in rabbits resulting from radiation exposure is contained in a recent communication by Sissons and Vaughan1. These workers described squamous cell carcinomas in the external auditory meat us of rabbits injected with strontium-90 at an early age. The available literature indicates a low natural incidence of tumours in rabbits2,3.

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References

  1. Sissons, H. A., and Vaughan, J., Nature, 185, 399 (1960).

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  2. Polson, C. J., J. Path. Bacteriol., 30, 603 (1927).

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  3. Feldman, W. H., in Neoplasms of Domestic Animals (W. B. Saunders Co., Philadelphia).

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GEORGE, L., MARKS, S. & BUSTAD, L. Fibrosarcoma in a Rabbit following β-Irradiation of the Skin. Nature 189, 770–771 (1961). https://doi.org/10.1038/189770a0

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