Abstract
NERURKAR et al. 1 have shown that administration of methionine either before or after X-irradiation decreases the damage caused to nucleic acid synthesis in irradiated rats. Post-irradiation administration of methionine appears to be more effective. Other assays have shown a lower increase in nitrogen, uric acid and in creatinine excretion in irradiated rats injected with methionine after irradiation2. The increase in uric acid excretion suggests excessive breakdown of nucleic acids as a result of cellular destruction. Treatment with methionine also results in a beneficial influence on the rate of growth after irradiation.
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Sahasrabudhe, M. B., Proc Second U.N. Internat. Conf. Peceful Uses Atomic Engergy, Geneva, 23, 94 (1958).
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BACQ, Z., BEAUMARIAGE, M. Inability of Methionine to affect Lethality in Mice and Rats exposed to X-Rays. Nature 186, 1064 (1960). https://doi.org/10.1038/1861064a0
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DOI: https://doi.org/10.1038/1861064a0
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