Abstract
SLATOR1 observed that alkyl halides and symmetrical ethylene di-halides react bimolecularly with sodium thiosulphate in water, but that the velocity of reaction with iodochlorethane and bromochlorethane was independent of the concentration of thiosulphate. The phenomenon under discussion is the transition in kinetic order of a reaction due to a very slight modification in the structure of one of the reactants. The problem has been discussed by E. D. Hughes and Ingold2, who reveal varied and more reliable instances of the same phenomenon. For example, β-phenylethyltrimethylammonium hydroxide decomposes bimolecularly, whereas halides of the corresponding p-nitro derivative decompose unimolecularly.
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MOELWYN-HUGHES, E. Dynamics and Mechanism of Aliphatic Substitution. Nature 133, 294 (1934). https://doi.org/10.1038/133294a0
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DOI: https://doi.org/10.1038/133294a0
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