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Change in stem cell source for hematopoietic stem cell transplantation (HSCT) in Europe: a report of the EBMT activity survey 2003

Summary:

This EBMT activity survey presents the status of hematopoietic stem cell transplantation (HSCT) in Europe 2003 and focuses on changes in stem cell source over the last decade. There were 21 028 first HSCT, 7091 allogeneic (34%), 13 937 autologous (66%) and 4179 additional re- or multiple transplants reported from 597 centers in 42 European countries in the year 2003. Main indications were leukemias (6613 (31%; 78% allogeneic)); lymphomas (11 571 (55%; 93% autologous)); solid tumors (1792 (9%; 92% autologous)) and nonmalignant disorders (898 (5%; 93% allogeneic)). In 1991, the vast majority of autologous and all allogeneic HSCT were still bone marrow (BM) transplants. Stem cell source changed rapidly to peripheral blood (PB) for autologous HSCT between 1992 and 1996. In 2003, 97% of autologous HSCT were PB derived. The change to PB for allogeneic HSCT followed 3 years later and occurred at a lower rate. In 2003, 65% of all allogeneic HSCT were PB derived. The change in stem cell source was not homogeneous. It was associated with donor type, main diagnosis, disease stage and it differed between European countries. In 2003, bone marrow remains a significant source of stem cells in some European countries for autologous HSCT and for nonmalignant disorders in allogeneic HSCT.

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References

  1. Thomas ED, Lochte Jr HL, Lu WC, Ferrebee JW . Intravenous infusion of bone marrow in patients receiving radiation and chemotherapy. N Engl J Med 1957; 257: 491–496.

    Article  CAS  Google Scholar 

  2. Thomas ED . Bone marrow transplantation: a review. Semin Hematol 1999; 36 (Suppl 7): 95–103.

    CAS  Google Scholar 

  3. Horowitz MM . Uses and growth of hematopoietic cell transplantation. In: Forman SJ, Blume KG, Thomas ED (eds). Hematopoietic Cell Transplantation, 3rd edn. Blackwell Scientific Publishers Inc.: London, New York, 2003, pp 9–15.

    Chapter  Google Scholar 

  4. Thomas ED, Storb R, Clift RA et al. Bone-marrow transplantation (second of two parts). N Engl J Med 1975; 292: 895–902.

    Article  CAS  Google Scholar 

  5. Goodman JW, Hodgson GS . Evidence for stem cells in the peripheral blood of mice. Blood 1962; 19: 702–714.

    CAS  PubMed  Google Scholar 

  6. Barnes DW, Loutit JF . Haemopoietic stem cells in the peripheral blood. Lancet 1967; 2: 1138–1141.

    Article  CAS  Google Scholar 

  7. Storb R, Epstein RB, Ragde H et al. Marrow engraftment by allogeneic leukocytes in lethally irradiated dogs. Blood 1967; 30: 805–811.

    CAS  PubMed  Google Scholar 

  8. McCredie KB, Hersh EM, Freireich EJ . Cells capable of colony formation in the peripheral blood of man. Science 1971; 171: 292–294.

    Article  Google Scholar 

  9. Anasetti C, Storb R, Longton G et al. Donor buffy coat cell infusion after marrow transplantation for aplastic anemia. Blood 1988; 72: 1099–1100.

    CAS  Google Scholar 

  10. Goerner M, Gooley T, Flowers ME et al. Morbidity and mortality of chronic GVHD after hematopoietic stem cell transplantation from HLA-identical siblings for patients with aplastic or refractory anemias. Biol Blood Marrow Transplant 2002; 8: 47–56.

    Article  CAS  Google Scholar 

  11. Thomas ED, Fefer A . Graft-versus-host disease. N Engl J Med 1979; 301: 556.

    CAS  PubMed  Google Scholar 

  12. Goldman JM, Catovsky D, Hows J et al. Cryopreserved peripheral blood cells functioning as autografts in patients with chronic granulocytic leukaemia in transformation. BMJ 1979; 1: 1310–1313.

    Article  CAS  Google Scholar 

  13. Haines ME, Goldman JM, Worsley AM et al. Chemotherapy and autografting for chronic granulocytic leukaemia in transformation: probable prolongation of survival for some patients. Br J Haematol 1984; 58: 711–721.

    Article  CAS  Google Scholar 

  14. Richman CM, Weiner RS, Yankee RA . Increase in circulating stem cells following chemotherapy in man. Blood 1976; 47: 1031–1039.

    CAS  Google Scholar 

  15. Socinksi MA, Cannistra SA, Elias A et al. Granulocyte-macrophage colony stimulating factor expands the circulating haemopoietic progenitor cell compartment in man. Lancet 1988; 1: 1194–1198.

    Google Scholar 

  16. Schmitz N, Linch DC, Dreger P et al. Randomised trial of filgrastim-mobilised peripheral blood progenitor cell transplantation vs autologous bone-marrow transplantation in lymphoma patients. Lancet 1996; 347: 353–357. Erratum in: Lancet 1996; 347: 914.

    Article  CAS  Google Scholar 

  17. Korbling M, Fliedner TM . The evolution of clinical peripheral blood stem cell transplantation. Bone Marrow Transplant 1996; 17 (Suppl 2): S4–S11.

    PubMed  Google Scholar 

  18. Gratwohl A, Baldomero H, Labar B et al. Accreditation Committee of the European Group for Blood and Marrow Transplantation (EBMT). Evolution of hematopoietic stem cell transplantation in Eastern and Western Europe from 1990 to 2003. A report from the EBMT activity survey. Croat Med J 2004; 45: 689–694.

    PubMed  Google Scholar 

  19. Kessinger A, Smith DM, Strandjord SE et al. Allogeneic transplantation of blood-derived, T cell-depleted hemopoietic stem cells after myeloablative treatment in a patient with acute lymphoblastic leukemia. Bone Marrow Transplant 1989; 4: 643–646.

    CAS  Google Scholar 

  20. Gluckman E, Broxmeyer HA, Auerbach AD et al. Hematopoietic reconstitution in a patient with Fanconi's anemia by means of umbilical-cord blood from an HLA-identical sibling. N Engl J Med 1989; 321: 1174–1178.

    Article  CAS  Google Scholar 

  21. Cohen Y, Nagler A . Umbilical cord blood transplantation – how, when and for whom? Blood Rev 2004; 18: 167–179.

    Article  Google Scholar 

  22. Champlin RE, Schmitz N, Horowitz MM et al. Blood stem cells compared with bone marrow as a source of hematopoietic cells for allogeneic transplantation. Blood 2000; 95: 3702–3709.

    CAS  Google Scholar 

  23. Powles R, Metha J, Kulkarni S et al. Allogeneic blood and bone marrow stem cell transplantation in hematological malignant diseases: a randomized trial. Lancet 2000; 355: 1231–1237.

    Article  CAS  Google Scholar 

  24. Blaise D, Kuentz M, Fortanier C et al. Randomized trial of bone marrow vs lenogastrim-primed blood cell allogeneic transplantation in patients with early-stage leukemia: a report from the Societe Francaise de Greffe de Moelle. J Clin Oncol 2000; 18: 537–546.

    Article  CAS  Google Scholar 

  25. Bensinger WI, Martin PJ, Storer B et al. Transplantation of bone marrow as compared with peripheral blood cells from HLA-identical relatives in patients with hematologic cancers. N Engl J Med 2001; 344: 175–181.

    Article  CAS  Google Scholar 

  26. Schmitz N, Beksac M, Hasenclever D et al. Transplantation of mobilized peripheral blood cells to HLA-identical siblings with standard risk leukemia. Blood 2002; 100: 761–767.

    Article  CAS  Google Scholar 

  27. Couban S, Simpson DR, Barnett MJ et al. A randomized multicenter comparison of bone marrow and peripheral blood in recipients of matched sibling allogeneic transplants for myeloid malignancies. Blood 2002; 100: 1525–1531.

    Article  CAS  Google Scholar 

  28. Ringden O, Labopin M, Bacigalupo A et al. Transplantation of peripheral blood stem cells as compared with bone marrow from HLA-identical siblings in adults with acute myeloid leukemia and acute lymphoblastic leukemia. J Clin Oncol 2002; 20: 4655–4664.

    Article  CAS  Google Scholar 

  29. Gratwohl A . Bone marrow transplantation activity in Europe 1990. Report from the European Group for Bone Marrow Transplantation (EBMT). Bone Marrow Transplant 1991; 8: 197–201.

    CAS  Google Scholar 

  30. Urbano-Ispizua A, Schmitz N, de Witte T et al. Allogeneic and autologous transplantation for haematological diseases, solid tumours and immune disorders: definitions and current practice in Europe. Bone Marrow Transplant 2002; 29: 639–646.

    Article  CAS  Google Scholar 

  31. Kvalheim G, Urbano-Ispizua A, Gratwohl A . Regulatory aspects and accreditation of the clinical use of hematopoietic progenitor cells in Europe. J Biol Regul Homeost Agents 2001; 15: 79–80.

    CAS  PubMed  Google Scholar 

  32. Rogers EM . Diffusion of innovations, 3rd edn. The Free Press: New York, 1983.

    Google Scholar 

  33. Gratwohl A, Passweg J, Baldomero H et al. for the Accreditation Committee of the European Group for Blood and Marrow Transplantation (EBMT). Economics, health care systems and utilisation of haematopoietic stem cell transplants in Europe. Br J Haematol 2002; 117: 451–468.

    Article  Google Scholar 

  34. Gratwohl A, Baldomero H, Passweg J, Urbano-Ispizua for the Accreditation Committee of the European Group for Blood and Marrow Transplantation (EBMT). Increasing use of reduced intensity conditioning transplants: report of the 2001 EBMT activity survey. Bone Marrow Transplant 2002; 30: 813–831.

    Article  CAS  Google Scholar 

  35. Gratwohl A, Schmid O, Baldomero H et al. Accreditation Committee of the European Group for Blood and Marrow Transplantation. Haematopoietic stem cell transplantation (HSCT) in Europe 2002. Changes in indication and impact of team density. A report of the EBMT activity survey. Bone Marrow Transplant 2004; 34: 855–875.

    Article  CAS  Google Scholar 

  36. De la Rubia J, Sanz MA . Autologous peripheral blood stem cell transplantation for acute leukaemias. Baillieres Best Pract Res Clin Haematol 1999; 12: 139–150.

    Article  CAS  Google Scholar 

  37. Uyl-de Groot CA, Ossenkoppele GJ, Buijt I, Huijgens PC . Costs of peripheral blood progenitor cell transplantation using whole blood mobilised by filgrastim as compared with autologous bone marrow transplantation in non-Hodgkin's lymphoma. Pharmacoeconomics 1999; 15: 305–311.

    Article  CAS  Google Scholar 

  38. Russell N, Gratwohl A, Schmitz N . The place of blood stem cells in allogeneic transplantation. Br J Haematol 1996; 93: 747–753.

    Article  Google Scholar 

  39. Barrett J, Childs R . Non-myeloablative stem cell transplants. Br J Haematol 2000; 111: 6–17.

    Article  CAS  Google Scholar 

  40. Slavin S . Smarter rather than stronger treatment of haematological malignancies and non-malignant indications for stem-cell transplantation. Lancet 2004; 364: 122–124.

    Article  Google Scholar 

  41. Haddad N, Rowe JM . Current indications for reduced-intensity allogeneic stem cell transplantation. Best Pract Res Clin Haematol 2004; 17: 377–386.

    Article  CAS  Google Scholar 

  42. Anderlini P, Przepiorka D, Seong D et al. Clinical toxicity and laboratory effects of granulocyte-colony-stimulating factor (filgrastim) mobilization and blood stem cell apheresis from normal donors, and analysis of charges for the procedures. Transfusion 1996; 36: 590–595. Erratum in: Transfusion 1997; 37: 109.

    Article  CAS  Google Scholar 

  43. Favre G, Beksac M, Bacigalupo A et al. European Group for Blood and Marrow Transplantation (EBMT). Differences between graft product and donor side effects following bone marrow or stem cell donation. Bone Marrow Transplant 2003; 32: 873–880.

    Article  CAS  Google Scholar 

Download references

Acknowledgements

The cooperation of all participating teams and their staff (listed in the Appendix), the EBMT secretariat (A Urbano-Ispizua, F McDonald, E McGrath, S Notely), the European EBMT Data Office in Paris (V Chesnel, NC Gorin), the EBMT Registry Subcommittee (P Ljungman, C Ruiz de Elvira), the French Registry SFGM (JP Jouet, Z Chir), the Dutch Registry TYPHON (A Hagenbeek, Av Biezen, M Sneets), the Austrian Registry (H Greinix, B Lindner), the Italian Registry (M Vignetti, A Bacigalupo, R Oneto, B Bruno), the German Registry (H Ottinger, M Westphal), the Swiss Registry (A Gratwohl, H Baldomero), the British Registry (K Towlson, J Apperley, M Wilson), the Turkish Registry (G Gurman, M Arat, F Arpaci, M Ertem), the Czech Registry (K Benesova, M Trnkova), and the Spanish Transplantation Office (ONT) (M Naya) is greatly appreciated. The authors also thank A Maerki for excellent secretarial assistance, as well as L John for technical assistance with data management.

The work was supported in part by the European Leukemia Net LSH-2002-2.2.0-3, by a grant from the Swiss National Research Foundation, 3200BO-106105/1, the Swiss Cancer League, the Regional Cancer League and the Horton Foundation. EBMT is supported by grants from the corporate members: Amgen Europe, Hoffmann-La Roche Ltd., Gilead Sciences, Baxter Oncology, Pharmacia Corporation, Chugai-Aventis, Fresenius HemoCare, SangStat, Schering AG, Gambro BCT, Elan Pharmaceuticals, Miltenyl Biotec GmbH, Therakos, Wyeth-Lederlé, Astra, Cobe International, Nextar, Liposome Co, Imtix, Octapharma, Stem Cell Technologies, ICN Pharmaceuticals and Bristol-Meyers Squibb.

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Correspondence to A Gratwohl.

Appendix

Appendix

List of transplant centres in 2003

Albania: no report

Andorra: no report

Armenia: no report

Algeria (1 team; 128 (132), 99/29)

Alger, Centre Pierre et Marie Curie, CIC 703, R Hamladji (128 (132), 99/29)

Austria (15 teams; 319 (406), 134/185)

Graz, Karl Franz University Hospital (onco), CIC 278, H Samonigg (0 (0), 0/0)

Graz, Karl Franz University Hospital (hem), CIC 308, W Linkesch (52 (65), 16/36)

Graz, Universitäts-Kinderklinik (hem, onco), CIC 593, Ch Urban (9 (10), 5/4)

Innsbruck, Universitätsspital (hem,onco), CIC 271, G Gastl, D Nachbaur (51 (68), 33/18)

Innsbruck, Universitätsspital, Internal Medicine (onco), CIC 516, E Woell (0 (0), 0/0)

Klagenfurt, General Hospital Klagenfurt, D Geissler, M Heistinger (5 (8), 0/5)

Linz, AO Krankenhaus (onco), 1 Medizin, MA Fridrik (4 (4), 0/4)

Linz, AOK der Elisabethinen, Internal Medicine, CIC 594, D Lutz, O Krieger (31 (43), 11/19)

Salzburg, LKA Salzburg (onco), CIC 356, R Greil (6 (10), 0/6)

Vienna, AKH, Universitätsklinik für Innere Medizin I (onco), CIC 227, HT Greinix, P Kalhs (82 (91), 38/44)

Vienna-Lainz, Krankenhaus der Stadt Wien-Lainz, 5 Med Onko, K Geissler, E Ulsperger (0 (0), 0/0)

Vienna, St Anna Kinderspital (hem, onco), CIC 528, H Gadner, C Peters (42 (45), 30/12)

Vienna, Hanusch-Krankenhaus (hem,onco), CIC 743, E Pittermann, E Koller (10 (13), 0/10)

Vienna, Donauspital, CIC 767, W Hinterberger (9 (15), 0/9)

Vienna, Wilhelminenspital (hem, onco), CIC 828, H Ludwig (18 (34), 0/18)

Azerbaijan (1 team; 1 (1), 1/0)

Baku, Azerbaijan Central Clinic Hospital, CIC 186, S Dincer (1 (1), 1/0)

Belarus, Republic of (2 teams; 66 (71), 17/49)

Minsk, Belorussian Center (hem, onco, peds), CIC 591, O Aleinikova (29 (31), 6/23)

Minsk, Hospital No 9, N Milanovitch (37 (40), 11/26)

Belgium (21 teams; 552 (687), 183/369)

Antwerpen, Stuivenberg ZH, CIC 339:1, P Zachée (37 (52), 6/31)

Antwerpen-Edegem, University Antwerpen (hem), CIC 339:2, W Schroyens (21 (28), 3/18)

Antwerpen, AZ Middelheim (hem), CIC 783, R de Bock (5 (6), 0/5)

Brugge, AZ St Jan (hem), CIC 506, D Selleslag, A Van Hoof, J Van Droogenbroeck, K Van Eygen (45 (58), 16/29)

Brussels, Institut Jules Bordet and the Children's University Hospital, CIC 215, D Bron, E Sariban, C Devalck, A Ferster (46 (70), 25/21)

Brussels, Clinique universitaire St Luc (hem, ads), CIC 234, A Ferrant (38 (43), 20/18)

Brussels, Clinique Universitaire St Luc (peds), CIC 234, C Vermylen (16 (17), 13/3)

Brussels, Cliniques Universitaires St Luc, (onco), JP Machiels (2 (3), 0/2)

Brussels, Hôpital Erasme (hem), CIC 596, W Feremans, A Kentos, M Lambermont, A Deweiwere (18 (21), 0/18)

Brussels, University Hospital (hem, onco), CIC 630, B Van Camp, Schots (20 (26), 9/11)

Brussels, The Clinic of Europe, CIC 779, C Dubois, C Laurent, S Marichal (0 (0), 0/0)

Charleroi, Hopital Notre-Dame (hem, onco), CIC 349, M André (13 (14), 1/12)

Charleroi, University Hospital (hem), CIC 804, A Triffet (8 (9), 0/8)

Gent, University Hospital (hem, ads, peds), CIC 744, LA Noens (41 (42), 20/21)

Haine St Paul, Hôpital de Jolimont (hem), CIC 234, A Delannoy, C Ravoot, N Straetmans (22 (24), 2/20)

Hasselt, Virgajesse Ziekenhuis (hem), CIC 632, D Vanstraelen, G Bries, V Madoe (31 (36), 0/31)

Leuven, University Hospital Gasthuisberg (hem, ads,peds), CIC 209, MA Boogaerts, P Vandenberghe, J Maertens (91 (112), 38/53)

Liège, CHR La Citadelle (hem, onco), CIC 353, B De Prijck (11 (14), 0/11)

Liège, University Hospital Sart-Tilman (hem), CIC 726, Y Béguin (44 (61), 24/20)

Roeselare, H Hartziekenhuis (hem,onco), CIC 646, F Van Aelst, J Tytgat, J Demol (14 (15), 1/13)

Yvoir, Clinique universitaire de Mont-Godinne (hem), CIC 234, C Doyen (29 (36), 5/24)

Bosnia-Herzegovina (1 team; 0 (0), 0/0)

Tuzla, University Clinical Centre of Tuzla (hem), M Malesevic (0 (0), 0/0)

Bulgaria (1 team; 15 (15), 6/9)

Sofia, Uni Hospital ‘Queen Johanna’ (peds hem-onco), CIC 346, D Bobev (15 (15), 6/9)

Croatia (2 teams; 110 (127), 25/85)

Zagreb, Clinic Hospital ‘Merkur’, CIC 159, B Jaksic, H Minigo (32 (34), 6/26)

Zagreb, Clinical Hospital Center, CIC 302, B Labar, D Nemet, M Mrsic (78 (93), 19/59)

Cyprus (1 team; 12 (12), 0/12)

Nicosia Makarious Hospital lll (hem), CIC 575, N Papaminas (12 (12), 0/12)

Czech Republic (10 teams; 503 (619), 142/361)

Brno, Masaryk University Hospital (ads, peds, hem, onco), CIC 597, J Vorlicek, J Mayer, Z Koristek (92 (126), 29/63)

Hradec Kralové, Charles University (hem), CIC 729, S Filip, M Blaha (42 (46), 6/36)

Olomouc, University Hospital (hem, onco), CIC 574, K Indràk (57 (60), 7/50)

Pilsen, Faculty Hospital (hem, onco), CIC 718, V Koza (73 (93), 36/37)

Prague, Clinical Haematology, Charles University, CIC 318, T Kozak (46 (50), 0/46)

Prague, Thomayer Memorial Hospital, CIC 375, J Abrahamova, J Nepomucka (16 (16), 0/16)

Prague, University Hospital Motol (peds hem), CIC 656, J Stary, E Kabickova (42 (54), 38/4)

Prague, University Hospital Motol (peds onco), E Kabickova, CIC 656 (14 (35), 0/14)

Prague, Institute of Hematology and Blood Transfusion, CIC 656, A Vitek, P Kobylka (44 (46), 26/18)

Prague, Charles University, CIC 745, M Trneny (77 (93), 0/77)

Denmark (3 teams; 209 (234), 58/151)

Aarhus, Amtssygehus (hem), CIC 634, E Segel (53 (54), 0/53)

Copenhagen, Rigshospitalet (hem), CIC 206, N Jacobsen (123 (142), 58/65)

Copenhagen, Herlev Hospital (hem), University, CIC 568, HE Johnsen (33 (38), 0/33)

Estonia (1 team; 12 (12), 4/8)

Tartu, University Hospital (hem, onco), CIC 746, H Everaus, A Kaare (12 (12), 4/8)

Finland (7 teams; 274 (310), 116/158)

Helsinki, Children's Hospital, CIC 219, U Pihkala, S Vettenranta (30 (33), 23/7)

Helsinki, University Central Hospital, Department of Medicine, CIC 515, T Ruutu (120 (133), 76/44)

Helsinki, University Hospital (onco), CIC 833, H Joensuu, R Janes (7 (7), 0/7)

Kuopio, Department of Medicine, University Hospital, CIC 396, E Jantunen, T Nousiainen (22 (22), 0/22)

Oulu, University Central Hospital (hem, onco), CIC 690, P Koistinen, T Turpeenniemi-Hujanen (20 (25), 0/20)

Tampere, University Hospital (ads, peds), CIC 635, E Koivunen, T Lehtinen, R Silvennoinen, M Arola (39 (47), 0/39)

Turku, University Central Hospital, CIC 225, K Remes (36 (43), 17/19)

France (75 teams; 2902 (3616), 717/2185)

Angers, Centre Hospitalier, CIC 650, N Ifrah, S François (51 (69), 7/44)

Angers, Paul Papin, Dr Gamelin*

Argenteuil, Centre hospitalier, M Urbajtel (15 (15), 7/8)

Besançon, Hôpital Jean Minjoz & Hôpital St Jacques (ads, peds), CIC 233, J-Y Cahn, P Herve, E Deconinck, PRohrlich (55 (69), 25/30)

Bobigny, Hôpital Avicenne (hem), P Casassus (22 (22), 0/22)

Brest, Centre Hospitalier, C Berthou*

Caen, Centre Hospitalier Régional, O Reman (21 (24), 3/18)

Caen, Hôpital Cote de Nacre (peds hem onco), P Boutard (1 (1), 0/1)

Caen, Centre Régional François Baclesse, AM Peny (30 (41), 0/30)

Clermont Ferrand, Centre Jean Perrin and CHU Hotel Dieu (ads, peds), CIC 273+589, J-O Bay, F Démeocq, P Travade (100 (125), 26/74)

Colmar, Hôpital civil, B Audhuy (13 (14), 0/13)

Corbeil Essonne, Hôpital Gilles de Corbeil, A Devidas (11 (11), 0/11)

Créteil, Hôpital H Mondor (hem), CIC 252, C Cordonnier, M Kuentz (43 (46), 20/23)

Dijon, Hôpital d'Enfants, D Caillot (51 (64), 0/51)

Dunkerque, Centre Hospitalier (hem), M Wetterwald*

Grenoble, Centre Hospitalier A Michallon (ads, allo peds), CIC 270, JJ Sotto, F Garban, P Drillat (65 (90), 22/43)

Grenoble, Centre Hospitalier (auto peds), D Plantaz, M Bost (6 (6), 4/2)

Lille, Hôpital Claude Huriez, CIC 277, F Bauters, JP Jouet (75 (93), 36/39)

Lille, Hôpital Jeanne de Flandre, Dr Nelken (1 (1), 0/1)

Lille, Centre Oscar Lambret (onco), Dr Depadt, Dr Defachelles (20 (20), 0/20)

Lille, Centre Hospitalier Saint Vincent, N Cambier (15 (17), 0/15)

Limoges, Centre Hospitalier Dupuytren (ads, hem), CIC 977, D Bordessoule, P Turlure (39 (45), 0/39)

Lyon, Centre Léon Bérard, CIC 241, P Biron, T Philip (67 (88), 0/67)

Lyon, Hôpital Edouard Herriot, CIC 671, M Michallet, AThiebaut, F Nicolini (63 (91), 34/29)

Lyon Sud (Pierre Benite), Centre Hospitalier, B Coiffier (125 (125), 0/125)

Lyon, Hôpital Debrousse, C Galambrun, Y Bertrand (19 (20), 19/0)

Marseille, Inst Paoli-Calmettes, CIC 230, D Blaise (245 (362), 24/221)

Marseille, Hôpital d'Enfants de la Timone (onco), CIC 301, C Coze, JL Bernard (11 (13), 0/11)

Meaux, Centre Hospitalier de Meaux, C Soussain (18 (18), 0/18)

Metz, Thionville Hôpital Notre-Dame de Bon-Secours (hem), V Dorvaux, B Christen (23 (27), 0/23)

Montpellier, CHU de Montpellier Hôpital Arnaud de Villeneuve, F Bernard (2 (2), 1/1)

Montpellier, Centre Rég De Lutte contre de Cancer, M Fabbro, J-B Dubois (7 (8), 0/7)

Montpellier, CHR Lapeyronie (hem), CIC 926, JF Rossi (106 (116), 19/87)

Mulhouse, Hôpital du Hasenrain, M Ojeda, Ph Hénon (16 (18), 0/16)

Nantes, Hotel Dieu (hem), CIC 253, JL Harousseau, N Milpied (111 (156), 28/83)

Nice, Hôpital de l'Archet 1, CIC 523, JP Cassuto, N Gratecos (45 (61), 16/29)

Nice, Fondation Lenval (peds), Dr Soler, Dr De Ricaud (2 (2), 0/2)

Nice, Centre Antoine Lacassagne, A Thyss (15 (22), 0/15)

Paris, Hôpital Necker (ads, hem), CIC 160, B Varet, C Bélanger, A Veil (73 (77), 39/34)

Paris, Hôpital Necker des enfants malades, CIC 201, A Fischer (36 (40), 36/0)

Paris, Hôpital St Louis (hem allo, ads, peds), CIC 207+ CIC 748, E Gluckman, H Esperou, A Baruchel, M-F Auclerc (104 (108), 104/0)

Paris, Hôpital St Louis (auto), CIC 805, G Gisselbrecht (57 (57), 0/57)

Paris, Hôpital St Louis (auto-leuk), CIC 960, H Dombret, L Degos, P Rousselot*

Paris, Hôpital St Louis (auto immuno-Haem), J-C Brouet, B Anruf, J-P Fermand (67 (67), 0/67)

Paris, Hôpital St Antoine (hem), CIC 213, C Gorin, L Fouillard (35 (46), 10/25)

Paris, Hôpital D'enfants Armand-Trousseau, CIC 213, G Leverger, A Auvrignon, L Douay (8 (9), 0/8)

Paris, Hôtel Dieu (hem), CIC 222, J-P Marie, B Rio (63 (72), 12/51)

Paris, Hôpital Pitié Salpétière (hem), CIC 262, J-P Vernant, V Leblond, N Dedhin (91 (94), 43/48)

Paris, Institut Curie (ads/onco/peds), CIC 702, J Michon*

Paris, Hôpital Tenon (onco), JP Lotz, CIC 747 (27 (47), 0/27)

Paris, Hôpital Robert Debré, K Yakouben, A Baruchel (18 (21), 15/3)

Paris, Hôpital Européen GP, JM Andrieu, C Le Maignan (20 (20), 0/20)

Paris, Hotel Dieu (onco), Professor Bernadou, L Chauvenet (0 (0), 0/0)

Paris, Hôpital d'Instruction des Armées Percy, Clamart, T de Revel, G Nedellec (18 (32), 2/16)

Paris, Hôpital Cochin, F Dreyfus, M Quarre*

Pessac, Hôpital Haut-Lévèque, CHU Bordeaux, CIC 267, J Reiffers, G Marit, R Tabrizi (106 (148), 32/74)

Poitiers, Hôpital la Miletrie, CIC 264, M Renaud (65 (95), 15/50)

Pontoise, Hospital Renè Dubois (onco), CIC 961, F Moruan (13 (18), 0/13)

Reims, Hopital Robert Debré (hem, onco), CIC 959, B Pignon, C Himberlin (21 (29), 0/21)

Rennes, CHRU, Clinique Médical Infantil, E Le Gall, V Gandemer (9 (10), 5/4)

Rouen, Centre Henri Becquerel, H Tilly, P Lenain (72 (91), 18/54)

Rouen, Hôpital Charles Nicolle, JP Vannier (11 (12), 5/6)

St Cloud, Centre René Huguenin, CIC 551, M Janvier (7 (8), 0/7)

Strasburg, Hôpital de Hautepierre, B Lioure (84 (101), 22/62)

Strasburg, Hospices Civils, Service de Pédiatrie 5, P Lutz (18 (18), 7/11)

Toulouse, Hôpital de Purpan (hem), CIC 624, M Attal, J-C Nogaro (107 (131), 35/72)

Toulouse, Hôpital de Purpan (peds), CIC 624, H Rubie (5 (5), 2/3)

Toulouse, Centre Claudius Régaud, H Roche, C Chevreau (8 (16), 0/8)

Tours, Hôpital Bretonneau (onco), CIC 272, P Colombat (102 (118), 0/102)

Valenciennes, Hosp De Valenciennes, M Simon*

Vandeuvre-les-Nancy, Hôpital d'Enfants, P Bordigoni (34 (49), 24/10)

Vandeuvre-les-Nancy, CHU Nancy-Brabois (hem auto), P Lederlin, F Witz (57 (74), 0/57)

Villejuif, Institut G Roussy (peds), CIC 503, O Hartmann, DValteau-Couanet (55 (99), 0/55)

Villejuif, Institut G Roussy (ads, hem), CIC 666, J-H Bourhis, C Boccaccio, J-M Vantelon*

Villejuif, Hôpital Paul Brousse, B Delmas-Marsalet (2 (2), 0/2)

Georgia: no report

Germany (107 teams; 3750 (4840), 1406/2344)

Aachen, Universitätsklinikum RWTH (hem, onco), Med Klinik lV, CIC 348, R Osieka, G Gehbauer (13 (16), 0/13)

Augsburg, Zentralklinikum (hem,onco), Med Klinik II, G Schlimok, M Sandherr (26 (31), 4/22)

Bad Saarow, Humaine Klinikum, G Schultze, H Fuss, P Frenzel (17 (17), 0/17)

Berlin, Universitätsklinikum der HU Charité Campus Virchow Klinikum (peds), CIC 336, W Ebell, G Gaedicke, J Kühl (36 (38), 29/7)

Berlin, Universitätsklinikum der HU Charité Campus Virchow Klinikum (ads, hem, onco), CIC 807, R Arnold (78 (94), 45/33)

Berlin, HELIOS Klinikum Berlin, Robert-Rössle Klinik (hem, onco), CIC 518, B Dörken, W-D Ludwig, M Hildebrandt (27 (34), 0/27)

Berlin, Universitäts-Klinik der FU Benjamin Franklin (hem, onco), CIC 590, E Thiel, L Uharek (60 (75), 22/38)

Berlin, Krankenhaus Neukölln (hem, onco), AC Mayr, C Kerschgens (0 (0), 0/0)

Bielefeld, Krankenanstalten Gilead (hem, onco), R Kolloch, U Kruempelmann, J Klempin (3 (4), 0/3)

Bielefeld, Franziska Hospital (hem, onco), HJ Weh, A Zumsprekel, T Nitsch (7 (12), 0/7)

Bochum, Knappschaftskrankenhaus (hem, onco), W Schmiegel, U Graeven (16 (26), 0/16)

Bonn, Rheinische Frierdrich-Wilhelms Universität (ads, hemonco), T Sauerbruch, I Schmidt-Wolf, C Ziske (22 (32), 0/22)

Bonn, Rheinische Frierdrich-Wilhelms Universität (peds, hemonco), U Bode, C Hasan (5 (8), 0/5)

Braunschweig, Städtisches Klinikum (hem, onco), CIC 674, B Wörmann, T Gabrysiak (22 (28), 0/22)

Bremen, Zentralkrankenhaus St Jürgenstrasse, CIC 602, H Rasche, C R Meier (15 (21), 0/15)

Bremen, DIAKO (hem, onco), T Wolff, KH Pflüger (19 (28), 0/19)

Chemnitz, Krankenhaus Küchwald (hem), F Fiedler, G Geissler, A Hänel (60 (69), 0/60)

Cottbus, Carl-Thiem Klinikum, Med Klinik ll (hem), H Steinhauer, N Peter (18 (30), 0/18)

Dessau, Städtisches Klinikum Dessau (hem, onco), M Plauth, A Florschütz (0 (0), 0/0)

Dortmund, St Johannes Hospital (hem, onco), H Plelken, M Nahler (4 (7), 0/4)

Dresden, Universitätsklinikum Carl Gustav Carus (hem, onco), CIC 808, G Ehninger, M Bornhäuser (132 (167), 73/59)

Duisburg, St Johannes Hospital, CIC 519, C Aul, J Anhuf (37 (42), 0/37)

Düsseldorf, Heinrich-Heine Universität; Medizinische Klinik (hem, onco) and St Antonius Hospital, Eschweiler (hem, onco), CIC 390, R Haas, G Kobbe, R Fuchs (92 (113), 38/54)

Düsseldorf, Heinrich-Heine Universität; Zentrum für Kinderheilkunde, CIC 651, U Göbel, D Dilloo (32 (58), 17/15)

Erlangen, Universitäts-Klinik für Kinder und Jugendliche (hemonco), CIC 809, W Rascher, W Holter, D Stachel (13 (13), 7/6)

Erlangen, Universität Erlangen-Nuremberg (hem, onco), Med Klinikum lll, CIC 809, M Gramatzki, J-R Kalden (31 (34), 8/23)

Essen, Universitätsklinikum (ads, peds), CIC 259, UW Schaefer, DW Beelen, W Havers, B Kremens, V Runde, O Basu (168 (182), 146/22)

Essen, Evangelisches Krankenhaus Essen-Werden GmbH (hem, onco), CIC 784, W Heit, M Wattad (39 (40), 0/39)

Essen, Universitätsklinikum (hem), U Dührsen, R Noppeney (18 (24), 0/18)

Essen, West German Cancer Center, S Seeber, P Bojko (35 (83), 0/35)

Frankfurt aM, Universitätklinikum dJW Goethe (hem, onco peds), CIC 138, T Klingebiel, D Schwabe (18 (21), 8/10)

Frankfurt aM, JW Goethe-Universität (ads), CIC 297, D Hoelzer, H Martin (76 (94), 31/45)

Frankfurt, KH Nordwest, A Knuth, E Jäger (1 (1), 0/1)

Frankfurt/Mainz, Städtisches Klinikum (ads), HG Derigs (9 (9), 0/9)

Freiburg i. Br., Universitätsklinik (ads, hem, onco), Med Klinik l, CIC 810, J Finke, R Mertelsmann (115 (138), 56/59)

Freiburg i. Br., UniversitätsKinderklinik (hem, onco), CIC 810, C Niemeyer, U Kontny, U Duffner (31 (33), 22/9)

Giesen, UniversitätsKinderklinik (hem, onco), CIC 326, A Reiter, W Wössmann (16 (23), 9/7)

Göttingen, Georg-August Universität (hem, onco), CIC 552, B Glass, L Trümper (76 (85), 33/43)

Greifswald, Ernst-Moritz-Arndt Universität (ads+peds), CIC 530, G Dölken, W Krüger (28 (31), 15/13)

Gütersloh, Städtkrankenhaus (hem, onco), R Depenbusch, C Gropp (3 (4), 0/3)

Hagen, Kath Krankenkaus (hem, onco), CIC 536, H Eimermacher, W Rethwisch (13 (23), 0/13)

Halle, Martin Luther Universität (hem, onco, ads), CIC 338, H-J Schmoll, H Wolf (16 (26), 0/16)

Halle, Martin Luther Universität (hem, onco, peds), CIC 654, S Burdach, A Wawer (3 (5), 1/2)

Hamburg, KH St George (hem, onco), CIC 153, P Dreger, N Schmitz (35 (46), 2/33)

Hamburg, Allgemeines Krankenhaus Altona (hem, onco), CIC 366, D, Braumann, H Salwender (35 (55), 0/35)

Hamburg, Eppendorf-Krankenhaus (hem, onco, ads, peds) CIC 614, AR Zander (118 (122), 101/17)

Hamburg, Eppendorf-Krankenhaus (hem, onco, ads), Med Klin ll, CIC 673, D Hossfeld (27 (33), 0/27)

Hameln, Kreiskrankenhaus Hameln (hem, onco), H Schmidt (7 (8), 0/7)

Hamm, St Marien Hospital (hem, onco), H Dürk (9 (9), 0/9)

Hamm, Evangelisches Krankenhaus (hem, onco), CIC 509, L Balleisen (0 (0), 0/0)

Hannover, Medizinische Hochschule (hem, onco, ads), CIC 295, A Ganser, B Hertenstein (89 (123), 46/43)

Hannover, Medizinische Hochschule (hem, onco, peds), CIC 295, K Welte, K Sykora (33 (37), 26/7)

Hannover, KH Siloah, CIC 342, H Kirchner, M Sosada (10 (10), 0/10)

Heidelberg, Ruprecht-Karls Universitäts-Poliklinik (hem, onco), CIC 524, AD Ho, H Schäfer (180 (286), 23/157)

Homburg/Saar, Universität des Saarlandes (hem, onco), CIC 785, J Schubert, M Pfreundschuh (56 (82), 19/37)

Idar-Oberstein, Klinik für Hämato-/Onkologie, CIC 592, AA Fauser, N Basara (35 (46), 20/15)

Jena, Klinik der FSU (hem, onco), Innere Medizin ll, CIC 533, HG Sayer, K Hoeffken (41 (61), 21/20)

Jena, Klinikum der FSU (hem, onco), Universitäts-Kinderklinik, CIC 750, F Zintl, D Fuchs (23 (25), 16/7)

Kaiserslautern, Westpfalzklinikum (hem), CIC 357, F-G Hagmann, H Link (5 (6), 1/4)

Karlsruhe, Städtisches Klinikum (hem, onco), CIC 290, J Fischer, T Kubin (14 (23), 0/14)

Kassel, Städtische Kliniken (hem, onco), E Steinhauer, M Wolf (2 (2), 0/2)

Kiel, Christian-Albrechts-Universität (hem, onco), CIC 256, M Kneba (66 (85), 22/44)

Köln, Universitäts-Klinik (ads, peds), CIC 534, V Diehl, Ch Scheid, F Berthold, T Simon (68 (79), 13/55)

Krefeld, Klinikum Krefeld, Med Klinik lll, S Helmer, T Frieling (9 (14), 0/9)

Leipzig, Universitäts-Klinik (hem, onco), CIC 389, D Niederwieser, R Krahl, W Pönisch (120 (139), 63/48)

Lemgo, Klinikum Lippe, HP Lohrmann (2 (2), 0/2)

Lübeck, MedUniversität (ads), CIC 367:1, J Fem, S Peters (20 (33), 0/20)

Lübeck, MedUniversität (peds), CIC 367:2, P Bucsky, Ch Schultz (1 (2), 0/1)

Lübeck, Städtisches KH Sud (hem, onco), Dr Heer-Sonderhoff, S Fetscher (17 (17), 0/17)

Magdeburg, Otto-von-Guericke Universität (hem, onco), CIC 359, A Franke, M Koenigsmann (18 (25), 0/18)

Magdeburg, Krankenhaus Altstadt, R Nowak, H Kroning (0 (0), 0/0)

Mainz, Johannes-Gutenberg-University (hem), Med Klin lll, CIC 786, C Huber, K Kolbe (72 (91), 25/47)

Mannheim, IlI Med Klinik, R Hehlmann, J Hastka (14 (16), 0/14)

Marburg, Med Universitätsklinik der Philipps Universität (hem, onco), CIC 645, A Neubauer, J Beyer (41 (60), 15/26)

Minden/Westfallen, Med Klinik (hem, onco), H Bodenstein, HJ Tischler (14 (15), 0/14)

Mönchengladbach, KH Maria Hilf ll, D Kohl, H-E Reis (12 (19), 0/12)

Munich, Klinikum Grosshadern der LMU (ads, hem, onco) CIC 513, H-J Kolb, W Hiddemann (117 (154), 79/38)

Munich, Klinikum Innenstadt der LMU (peds, hem, onco), CIC 513, C Bender-Götze (18 (20), 13/5)

Munich, SKH München-Harlaching (hem, onco), CIC 664, R Hartenstein, M Hentrich (14 (21), 0/14)

Munich, Städt Krankenhaus Schwabing (hem, onco, peds), P Emmerich, L Stengel-Rutkowski (5 (5), 3/2)

Munich, Klinikum Innenstadt der LMU, C Straka, D Schlöndorff (27 (40), 0/27)

Munich, SKH München-Schwabing (hem, onco), Ch Nerl, N Fischer, C Waterhaus (27 (29), 0/27)

Munich, Klinikum rechts der Isar (hem, onco), CIC 558, C Peschel, C v Schilling (46 (63), 4/42)

Münster, Westfälische Wilhelms-Universitäts Kinderklinik (hem, onco), CIC 505, H Jürgens, J Vormoor, T Huf (25 (30), 20/5)

Münster, Westfälische Wilhelms-Universitäts Klinik (hem, onco), Innere Med CIC 680, W Berdel, J Kienast (81 (98), 28/53)

Neuss, Lukaskrankenhaus (hem, onco), P Czygan, J Streuss (0 (0), 0/0)

Nürnberg, Städt Klinikum (hem, onco), CIC 625, H Wandt, W Gallmeier, K Schäfer (68 (79), 23/45)

Oldenburg, Klinikum Oldenburg (hem, onco), CIC 749, B Metzner, H Illiger (53 (89), 0/53)

Potsdam, Klinikum Ernst von Bergmann (hem, onco), A Haas, R Pasold (15 (23), 0/15)

Regensburg, Universitäts Klinikum (hem, onco), CIC 787, E Holler, R Andreesen, A Reichle (90 (125), 40/50)

Rostock, Universitäts Klinikum (hem, onco), CIC 585, M Freund, J Casper (52 (81), 17/35)

Siegen, St Marien Krankenhaus (hem, onco), CIC 135, T Gaska, W Gassmann (6 (10), 0/6)

Stuttgart, Robert-Bosch-Krankenhaus (hem, onco), CIC 145, S Martin, W Aulitzky (33 (38), 3/30)

Stuttgart, Olgahospital (hem, onco), Pädiatrisches Zentrum, CIC 701, J Treuner, E Koscielniak (4 (4), 0/4)

Stuttgart, Bürgerhospital, W Grimminger, H Mergenthaler (15 (24), 0/15)

Stuttgart, Diakonissen Krankenhaus, E Heidemann, J Kaesberger (3 (5), 0/3)

Stuttgart, Katharinenhospital (onco), J Schleicher, H-G Mergenthaler (14 (20), 0/14)

Tübingen, Medizinische Universitäts-Klinik (hem, onco), CIC 223, L Kanz, H Einsele, C Faul (98 (134), 33/65)

Tübingen, Medizinische Universitäts-Klinik (hem, onco), Abteilung Pädiatrie, CIC 535, J Greil, D Niethammer (29 (33), 24/25)

Ulm, Medizinische Universitäts-Klinik (hem, onco), CIC 204, HDöhner, D Bunjes (106 (135), 46/60)

Ulm, Kinderklinik der Universität, CIC 204, W Friedrich, K Debatin, A Schultz (31 (34), 30/1)

Villingen, Klinikum Villingen (6 (7), 0/6)

Wiesbaden, Deutsche Klinik für Diagnostik, CIC 311, R Schwerdtfeger, M Schleining, H Baurmann (76 (80), 67/9)

Wiesbaden, Dr Horst-Schmidt Klinikum (hem, onco), CIC 586, N Frickhofen, B Jung (8 (17), 0/8)

Wuppertal, Klinikum Wuppertal GmbH (hem, onco), A Raghavachar (0 (0), 0/0)

Würzburg, Universitätsklinikum Würzburg (hem, onco, ads), CIC 712, K Wilms, F Weissinger (34 (44), 0/34)

Würzburg, Universitätsklinikum Würzburg (peds), P Schlegel (6 (8), 0/6)

Greece (11 teams; 197 (215), 76/121)

Alexandroupolis, Thrace University Medical School (Haem), CIC 681, G Bourikas, D Pantelidou (6 (6), 0/6)

Athens, Laikon General Hospital, CIC 328, Y Rombos, D Boutsis, V Kalotychou (8 (9), 0/8)

Athens, Medical Center (hem), CIC 603, A Pigadito (2 (2), 0/2)

Athens, University of Athens, CIC 604, I Dervenoulas (3 (3), 0/3)

Athens, Evanghelismos Hospital (hem), CIC 622, D Karakassis, A Skandalis, N Harhalakis, E Nikiforakis (41 (47), 27/14)

Athens, Diagnosis & Therapy Centre “Hygeia” (hem), Maroussi, CIC 643, G Karianakis (9 (9), 0/9)

Athens, Hellenic Cancer Institute St Savas (onco), CIC 751, A Efremedis, M Stamatellou, K Papanastassiou, M Pouli (42 (47), 7/35)

Athens, “Aghia Sophia” Children's Hospital, CIC 752, S Graphakos (26 (26), 17/19)

Crete, University Hospital of Heraklion (peds, hem-onco), CIC 352, M Kalmanti (0 (0), 0/0)

Patras, University Medical School (hem), CIC 281, NC Zoumbos, M Tiniakou (8 (10), 1/7)

Thessaloniki, The George Papanicolaou General Hospital (hem), CIC 561, AS Fassas (52 (56), 24/28)

Hungary (4 teams; 171 (180), 38/133)

Budapest, National Medical Centre (hem), CIC 504, A Poros, A Barta, E Torbagyi (38 (41), 10/28)

Budapest, Szent Laszlo Hospital, CIC 739, T Masszi, P Reményl, G Kriván (85 (91), 21/64)

Miskolc, Postgraduate Medical School (peds), CIC 599, N Kalman, G Marton (18 (18), 7/11)

Pécs, University of Pécs, Internal Medizine, CIC 682, H Losonczy, M Dávid, Á Szomor (30 (30), 0/30)

Iceland (1 team; 0 (0), 0/0)

Reykjavik, National University Hospital (hem), CIC 605, S Reykdal (0 (0), 0/0)

Iran (2 teams; 214 (216), 154/60)

Shiraz, Nemazee Hospital (hem, onco), CIC 188, M Ramzi (27 (27), 6/1)

Teheran, Shariati Hospital (hem, onco), CIC 633, A Ghavamzadeh (187 (189), 128/59)

Ireland (6 teams; 127 (138), 46/81)

Cork, University Hospital, P Cotter (4 (4), 0/4)

Dublin, St James's Hospital (hem), CIC 257, SR McCann (88 (97), 37/51)

Dublin, St Vincent's Hospital (hem, onco), CIC 541, J Crown, K Murphy (8 (8), 0/8)

Dublin, Our Lady's Hospital of Sick Children, Crumlin, CIC 774, A O'Meara (17 (19), 9/8)

Dublin, Mater Hospital (hem), B Otridge (0 (0), 0/0)

Galway, University College Hospital, M Murray (10 (10), 0/10)

Israel (6 teams; 434 (529), 208/226)

Haifa, Rambam Medical Center (hem, ads, peds), CIC 345, J Rowe (130 (145), 52/78)

Jerusalem, Hadassah University Hospital (ads, peds), CIC 258, R Or, S Slavin (113 (140), 68/45)

Petach-Tikva, Children's Medical Center, CIC 755, J Stein (39 (41), 24/15)

Revohot, Kaplan Hospital (hem), CIC 327, A Berribi (12 (13), 0/12)

Tel Aviv, Sourasky Medical Center, CIC 161, E Naparstek (22 (26), 4/18)

Tel Hashomer, Chaim Sheba Medical Center (hem ads, peds) CIC 754+CIC 572, A Nagler, A Shimoni, A Toren, H Golan, B Bielorai (118 (164), 60/58)

Italy (95 teams; 3326 (4295), 1002/2324)

Alessandria, SS Antonio e Biagio e C Arrigo (hem), CIC 825, A Levis, A Allione, M Pini, F Salvi (36 (45), 80/28)

Ancona, Nuovo Ospedale Torrette (hem), CIC 788, P Leoni, A Olivieri (37 (51), 11/26)

Avellino, AOS Giovanni Di Guglieimo (hem), CIC 789, E Volpe, N Cantore (34 (36), 5/29)

Avezzano, Ospedale Civile di Avezzano, F Recchia (4 (5), 0/4)

Aviano, CRO Aviano (onco), CIC 162, M Michieli, M Rupolo, M Mazzucato, F Lollo 29 (35), 0/29)

Bari, Universita degli Studi di Bari (hem), CIC 649, V Pavone, V Liso (56 (73), 0/56)

Bergamo, Ospedale Riuniti, CIC 658, T Barbui, A Rambaldi (91 (127), 24/67)

Bologna, St Orsola-Malpighi (hem, onco), CIC 240, G Bandini, F Bonifazi, M Baccarani (131 (163), 34/97)

Bologna, St Orsola-Malpighi, Oncologia Medica, CIC 657, A Martoni, C Zamagni (5 (7), 0/5)

Bologna, Poli S Orsola, Clinica pediatrica III, CIC 790, A Pession (29 (36), 12/17)

Bolzano, Ospedale S Maurizio (hem), CIC 299, M Casini, P Fabris, P Coser (44 (82), 5/39)

Brescia, Ospedali Civili, CIC 288, G Rossi, C Almici (56 (73), 0/56)

Brescia, Universitá degli Studi di Brescia (peds), CIC 741, F Porta, A Ugazio (23 (24), 19/4)

Brindisi, Ospedaliera ‘A Di Summa’, Perrino Hospital (hem), CIC 920, G Quarta, S Pinna (10 (10), 0/10)

Cagliari, Ospedale A Businco (hem), CIC 791, P Dessalvi (41 (55), 12/29)

Cagliari, BMT Center CIC 811, G La Nasa, L Contu (23 (26), 12/11)

Cagliari, Ospedale per le Microcitemie (peds), CIC 812, F Argiolu, A Cao (10 (12), 10/0)

Catania, Ospedale Ferrarotto (hem), CIC 792, R Giustolisi, G Milone (54 (57), 19/35)

Cremona, Ospedale Maggiore (hem), Medicina II, CIC 226, S Morandi, P Spedini, M Tajana, C Fiamenghi (10 (12), 0/10)

Cuneo, Hospital S Croce E Carle (hem), CIC 606, A Gallamini, M Grasso (16 (22), 2/14)

Ferrara, St Anna Hospital (hem), CIC 330, G Castoldi, F Lanza, S Moretti, GM Rigolin, R Spanedda (19 (20), 0/19)

Firenze, Ospedale di Careggi (hem), CIC 304, A Bosi, S Guidi (73 (80), 23/50)

Firenze, Azienda Ospedale, ‘AMeyer’, CIC 600, L Faulkner (17 (25), 3/14)

Forli, Morgagni-Pierantoni Hospital (onco), CIC 298, GL Frassineti, D Amadori (9 (19), 0/9)

Genova, Università, CIC 139, F Patrone, A Ballestrero (32 (38), 0/32)

Genova, Ospedale S Martino (hem), CIC 217, A Bacigalupo, G Santini (82 (87), 80/2)

Genova, Istituto Giannina Gaslini (hem, onco), CIC 274, G Dini (54 (73), 17/37)

Latina, Ospedale S Maria Goretti, A De Blasio, E Zappone (14 (19), 0/14)

Messina, Policlinico Universitario (onco), CIC 669, V Pitini (9 (11), 0/9)

Milano, Ospedale di Niguarda (onco ST), CIC 184, S Siena, P Pedrazzoli, R Schiavo (46 (57), 7/39)

Milano, Ospedale Maggiore di Milano, CIC 265, G Lambertenghi Deliliers (34 (41), 24/10)

Milano, Ospedale Fatebenefratelli e Oftalmico (onco), CIC 269, A Scanni, C Bianchi, D Pedretti (1 (1), 0/1)

Milano, Ospedale di Niguarda (hem), CIC 294, P Marenco, R Cairoli (65 (76), 17/48)

Milano, Istituto Europeo di Oncologia, CIC 331, G Martinelli (59 (78), 10/49)

Milano, 1st Clinico Humanitas (hem-onco), CIC 354, A Santoro, L Castagna (54 (85), 6/48)

Milano, Istituto Nazionale Tumori (ads), CIC 616, A Gianni, P Corradini (71 (141), 10/61)

Milano, Ist Nazionale Tumori di Milano (onco, peds), CIC 616, R Luksch (26 (45), 0/26)

Milano, S Carlo Borromeo Hospital (onco), CIC 683, L Tedeschi (4 (4), 0/4)

Milano, Istituto Scientifico HS Raffaele, CIC 813, M Bregni (63 (81), 28/35)

Modena, University of Modena (hem, onco), CIC 543, F Narni, A Donelli, R Sabbatini (31 (57), 4/27)

Monza, Ospedale S Gerardo (peds), CIC 279, C Uderzo (25 (30), 16/9)

Monza, Ospedale S Gerardo de' Tintori, CIC 544, P Pioltelli, E Pogliani (44 (58), 8/36)

Napoli, Div Di Oncologia, CIC 313, C Battista, G Pacilio, B Chiurazzi, G Iodice (9 (14), 0/9)

Napoli, Hospital ‘Pausilipon’ (hem peds), V Poggi, M Ripaldi (15 (16), 9/6)

Napoli, Cardarelli Hospital (hem), CIC 607, F Ferrara (53 (62), 2/51)

Napoli, Cardarelli Hospital (hem), CIC 837, V Mettivier (17 (21), 0/17)

Napoli, Università Federico ll (hem), CIC 766, B Rotoli, C Selleri, G De Rosa (37 (41), 14/23)

Noale, Civic Hospital (onco), CIC 563, O Vinante, G Azzarello (11 (14), 9/2)

Nuoro, Ospedale San Francesco (hem), CIC 793, A Gabbas, A Palmas (13 (17), 0/13)

Orbassano, Ospedale San Luigi Orbassano, CIC 378, G Saglio, A Guerrasio (24 (44), 1/23)

Padova, Centro Leucemie Infantili, CIC 285, C Messina, S Cesaro, L Zanesco, S Varotto (20 (28), 15/5)

Padova, Centro Oncologia Regionale, CIC 319, S Aversa, S Monfardini (15 (17), 4/11)

Palermo, Ospedale V Cervello (hem), CIC 392, R Scimè, A Cavallaro (47 (63), 10/37)

Palermo, Ospedale ‘La Maddalena’ (hem, onco), CIC 692, M Musso, F Porretto, A Crescinanno (41 (67), 8/33)

Palermo, Uni degli studi di Palermo (hem), CIC 814, G Mariani (18 (20), 0/18)

Parma, Cattedra di Ematologia, Univ of Parma, CIC 245, V Rizzoli (12 (18), 0/12)

Pavia, Policlinico S Matteo (hem), CIC 286, EP Alessandrino(64 (69), 21/43)

Pavia, Policlinico St Matteo (hem, onco, peds), CIC 557, F Locatelli (77 (94), 60/17)

Pavia, Policlinico St Matteo (onco), CIC 562, M Danova (18 (18), 0/18)

Pavia, Fondazione S Maugeri (onco), CIC 771, A Zambelli, G Robustelli della Cuna (7 (13), 1/6)

Perugia, Policlinico Monteluce (onco), CIC 573, AM Liberati, F Grignani (23 (26), 0/23)

Perugia, Policlinico Monteluce (hem), Università, CIC 794, MF Martelli, F Aversa, A Tabilio (119 (125), 52/67)

Perugia, Silvestrini Hospital, A Amici (0 (0), 0/0)

Pesaro, Ospedale San Salvatore, CIC 529, G Visani, G Lucarelli (64 (66), 44/20)

Pescara, Ospedale Civile (hem), CIC 248, P di Bartolomeo (39 (43), 27/12)

Piacenza, Ospedale Civile (hem, onco), CIC 163, L Cavanna (12 (18), 2/10)

Pisa, St Chirara Hospital (ads, onco) CIC 320, C Bengala (9 (9), 1/8)

Pisa, University of Pisa (Ads hem, peds hem+onco), CIC 795, P Macchia, M Petrini (57 (84), 13/44)

Ravenna, Ospedale Civile (hem, onco), CIC 306, G Rosti (25 (41), 0/25)

Reggio di Calabria, Azienda Ospedale “Riuniti e Morelli”, CIC 587, P Iacopino (57 (74), 12/45)

Reggio Emilia, Arcispedale S Maria Nuova (hem), CIC 660, L Gugliotta (17 (22), 7/10)

Rimini, Ospedale Infermi Rimini (hemonco), P Fattori (12 (15), 0/12)

Rionero in Vulture, Ospedale Oncologico Regionale, CIC 185, N Di Renzo (13 (15), 0/13)

Roma, Regina Elena Cancer Institue (hem, onco), CIC108, M Petti (2 (3), 0/2)

Roma, Università “La Sapienza”, CIC 232, W Arcese, F Mandelli, G Meloni (100 (109), 35/65)

Roma, Ospedale S Camillo (hem), CIC 287, I Majolino, A Locasciulli (38 (47), 20/18)

Roma, Università Cattolica (hem), CIC 307, S Cuore, S Sica, G Leone (21 (21), 9/12)

Roma, Ospedale Bambino Gesu (hem), CIC 315, G De Rossi (4 (4), 2/2)

Roma, Università S Eugenio (hem), CIC 756, W Arcese, P Fabritiis (51 (55), 18/33)

Roma, Ospedale Bambino Gesu (onco), CIC 796, A Donfrancesco (19 (23), 0/19)

San Giovanni Rotondo, Hospital Casa Sollievo Sofferenza (onco), CIC 314, M Aieta*

San Giovanni Rotondo, Hospital Casa Sollievo Sofferenza (peds), CIC 350, P Paolucci, M Pastore (4 (8), 0/4)

San Giovanni Rotondo, Hospital Casa Sollievo Sofferenza (hem), CIC 526, M Corsetti, M Greco (51 (68), 19/32)

Siena, Ospedale Sclavo (hem), CIC 321, F Lauria (41 (46), 12/29)

Taranto, Ospedale Nord (hem), CIC 332, P Mazza, G Palazzo, B Amurri (60 (62), 17/43)

Torino, Azienda Ospedaliera S Giovanni, CIC 231, M Falda, F Locatelli (63 (91), 28/35)

Torino, Ospedale Regina Margherita (peds), CIC 305, E Madon, F Fagioli, E Vassallo (45 (63), 18/27)

Torino, Ospedale Mauriziano Umberto 1, IRCC, CIC 377, M Aglietta, A Capaldi, F Carnevale (22 (25), 10/12)

Torino, Ospedale S Giovanni (hem), CIC 696, M Boccadoro, M Massaia, C Tarella, B Benedetto, D Caracciolo, A Pileri (60 (130), 14/46)

Trieste, Istituto per I'Infanzia, Clinical Pediatrica, CIC 525, M Andolina (10 (10), 7/3)

Udine, Policlinico Universitario (hem), CIC 705, R Fanin (99 (131), 32/67)

Venezia, Ospedale Civile Riuniti di Venezia (hem), CIC 502, T Chisesi, M Vespignani, M Chinello (18 (28), 1/17)

Verbania Pallanza, Ospedale di Verbania, M Bersi*

Verona, Policlinico di Borgo Roma (hem, onco), CIC 623+CIC 514, G Perona, F Benedetti, G Cetto (57 (60), 14/43)

Vicenza, Ospedale S Bortolo (hem), CIC 797, R Raimondi, F Rodeghiero (45 (60), 8/37)

Latvia: no report

Liechtenstein: no report

Lithuania: (2 teams; 49 (54), 20/29)

Vilnuis, University Hospital Santariskiu Klinikos (hem), I Trociukas (42 (47), 17/25)

Vilnuis, University Children's Hospital (hem, onco), CIC 508, J Rascon (7 (7), 3/4)

Luxemburg (1 team*)

Esch-Alrette, Hopital de la Ville Esch/Alzette, CIC 545, F Le Moine*

Macedonia: (1 team; 22 (22), 3/19)

Skopje, Medical Faculty (hem), CIC 381, B Georgievski (22 (22), 3/19)

Malta: no report

Moldova: no report

Monaco: no report

Netherlands (13 teams; 688 (791), 269/419)

Amsterdam, Academic Medical Center (ads, peds), CIC 247, J van der Lelie, H van den Berg (peds) (45 (49), 7/38)

Amsterdam, Free University Hospital (hem), CIC 588, GJ Ossenkoppele (68 (96), 12/56)

Amsterdam, The Netherlands Cancer Institute, S Rodenhuis J Baars (17 (32), 0/17)

Enschede, The Medisch Spectrum Twente, CIC 360, Dr Schaafsma (20 (20), 0/20)

Groningen, University Hospital (hem), CIC 546, G van Imhoff, E Vellenga (41 (45), 10/31)

The Hague, Leyenburg Hospital, CIC 547, PW Wijermans (16 (22), 0/16)

Leiden, University Medical Centre (ads, peds), CIC 203, R Willemze, M Egeler (86 (96), 55/31)

Maastricht, University Hospital (hem, onco), CIC 565, HC Schouten, J Wagstaff (54 (54), 22/32)

Nieuwegein, St Antonius Hospital, CIC 200, D Biesma, G Veth, O de Weerdt (12 (14), 0/12)

Nijmegen, University Hospital (ads, peds, onco), CIC 237, A Schattenberg, L Beex, P Hoogerbrugge (102 (102), 49/53)

Rotterdam, Dr Daniel den Hoed Cancer Center, CIC 246, JJ Cornelissen (109 (118), 43/66)

Utrecht, University Hospital (hem, ads, peds), CIC 239, LF Verdonck, NM Wulffraat (111 (136), 71/40)

Zwolle, Isala Kliniecken/Sophia Ziekenhuis, CIC 548, M von Marwijk Kooy (7 (7), 0/7)

Norway (5 teams; 126 (129), 37/89)

Bergen, Haukelands Sjukhus, P Ernst (12 (13), 0/12)

Oslo, Rikshospitalet, CIC 235, D Albrechtsen, L Brinch (56 (58), 37/19)

Oslo, The Norwegian Radium Hospital (onco), CIC 782, S Kvaloy (29 (29), 0/29)

Oslo, Ullevals Sjukhus (haem), F Wisslöf, J-M Tangen (11 (11), 0/11)

Trondheim, St Olavs Hospital, J Hammerstrom, A Waage (18 (18), 0/18)

Poland (17 teams; 706 (802), 268/438)

Bydgoszcz, Medical University (peds, hem, onco), CIC 764, M Wysocki, J Stycznski (1 (1), 1/0)

Gdansk, Medical University (hem), CIC 799, A Hellmann (57 (58), 27/30)

Katowice, Silesian Medical Academy (hem), CIC 677, J Holowiecki (142 (168), 62/80)

Krakow, Jagiellonian University (hem), CIC 553, A Skotnicki (51 (55), 18/33)

Krakow, Polish-American Children's Hospital, JUMC, CIC 507, M Ratajczak (6 (6), 0/6)

Lodz, Medical University of Lodz (hem), CIC 171, T Robak (17 (17), 0/17)

Lublin, Children's University Hospital (hem, onco), CIC 678, J Kowalczyk (27 (28), 15/12)

Lublin, University Medical School (hem, onco), CIC 695, A Dmoszynska, M Wach, A Walter-Croneck, W Legiec (31 (40), 0/31)

Poznan, Institute of Pediatrics, CIC 641, J Wachowiak (14 (19), 12/2)

Poznan, K Marcinkowski University (hem), CIC 730, M Komarnicki (64 (66), 23/41)

Warsaw, Institute of Haematology and Blood Transfusion, CIC 693, B Marianska, L Konopka, B Nasilowska (18 (18), 5/13)

Warsaw, Maria Sklodowska-Curie, Centre of Oncology, CIC 800, J Walewski (47 (54), 2/45)

Warsaw, Central Hospital Military Medical Academy (hem, onco), CIC 816, P Rzepecki, K Sulek, C Szczylik (36 (41), 7/29)

Warsaw, Central Clinical Hospital (hem, onco), CIC 954, W Wiktor-Jedrzejczak, A Deptala, M Rokicka (49 (77), 18/31)

Wroclaw, K Diuske Hospital, CIC 538, A Lange (62 (66), 31/31)

Wroclaw, Medical Academy (hem), CIC 699, K Kuliczkowski (16 (16), 2/14)

Wroclaw, University of Medicine (peds, hem, onco), CIC 817, A Chybicka (68 (72), 45/23)

Portugal (6 teams; 243 (273), 87/146)

Coimbra, University Hospital, CIC 164, N Costa (13 (13), 0/13)

Lisbon, Instituto Portugues de Oncologia, CIC 300, M Abecasis, F Leal Costa (52 (69), 20/32)

Lisbon, Hospital de Santa Maria, CIC 636, J Alves do Carmo, F de Lacerda (41 (44), 32/9)

Lisbon, Hospital de St Antonio dos Capuchos, CIC 826, A Botelho de Sousa (33 (33), 0/33)

Porto, Instituto Portugues de Oncologia, CIC 291, P Pimentel, F Campilho (79 (88), 35/44)

Porto, Hospital S Joao (hem onco), CIC 329 (merged with CIC 572, F Principe, JE Guimaraes (25 (26), 0/25)

Romania: (3 teams; 13 (13), 2/11)

Bucharest, Fundeni University Hospital (hem), CIC 296, AD Moicean, D Colita, C Arion (3 (3), 1/2)

Targu-Mures, Sectia Clinica de Hematologie, CIC 178, I Benedek (8 (8), 0/8)

Timisoara, University of Medicine (lll peds Hem/Onco), CIC 174, M Serban (2 (2), 1/1)

Russia (13 teams; 194 (212), 61/133)

Ekaterinburg, City Hospital No 7, LB Filatov (7 (7), 1/6)

Ekaterinburg, Regional Hospital No 1, TS Konstantinova, VA Shalaev (10 (11), 2/8)

Moscow, Russian Children's Hospital (hem), CIC 694, A Maschan, E Skorobogato, E Pachanov (38 (42), 27/11)

Moscow, Cancer Research Center, CIC 757, V Ptuschkin (25 (26), 0/25)

Moscow, Institute of Biophysics, AE Baranov (6 (7), 0/6)

Moscow, Cancer Research Center peds Hem/onco, G Mentrevich (24 (24), 2/22)

Moscow, Research Hematology Center of RAS, VG Savtchenko (21 (23), 8/13)

Novosibirsk, Insitute of Clinical Immunology, CIC 376, I Lisukov (12 (12), 1/11)

Samara, Regional Hospital, VA Rossiev (14 (14), 2/12)

St Petersburg, Clinical Center for Advanced Medical Tech, CIC 370, E Podoltseva, V Soldatenkov, O Ryasnyanskaya (4 (9), 1/3)

St Petersburg, Military Medical Academy (hem), CIC 520, A Novik*

St Petersburg, Research Institute of Hematology, KM Abdulkadirov (6 (7), 2/4)

St Petersburg, State Pavlov Medical University (hem), CIC 725, BV Afanassiev, L Zubarovskaya (27 (30), 15/12)

San Marino: no report

Saudi Arabia (2 teams; 170 (179), 128/42)

Riyadh, King Faisal Specialist Hospital and Research centre (onco, ads hem), CIC 3971, M Al Jurf (99 (104), 59/40)

Riyadh, King Faisal Specialist Hospital and Research centre (peds hem, onco), CIC 3972, M Ayas (71 (75), 69/2)

Slovakia (4 teams; 118 (125), 24/94)

Bansra Bystrica, Roosevelt Hospital (hem), CIC 333, I Markuljak, E Kralikova (13 (16), 0/13)

Bratislava, National Cancer Institute, CIC 560, J Lakota (70 (73), 8/62)

Bratislava, University Hospital (hem), CIC 610, M Mistrik (25 (26), 11/14)

Bratislava, University Hospital, 2nd Children's Clinic, CIC 684, J Lukac (10 (10), 5/5)

Slovenia (1 team; 35 (43), 9/26)

Ljubljana, University Medical Centre (hem), CIC 640, J Pretnar (35 (43), 9/26)

Spain (73 teams; 1677 (1868), 455/1222)

Alicante, Hospital General, C Rivas-Gonzales*

Barcelona, Hospital Clinic (hem, onco), CIC 214, E Montserrat, E Carreras (65 (73), 25/40)

Barcelona, Santa Creu I Sant Pau (adults), CIC 260, J Sierra, S Brunet (88 (112), 23/65)

Barcelona, Santa Creu I San Pau (peds), CIC 260, I Badell Serra, J Cubells-Riero (6 (6), 2/4)

Barcelona, Santa Creu I Sant Pau (onco), CIC 260, Dr JJ Lopez, C Solà*

Barcelona, Hospital M Infantil, CIC 527, J Ortega (38 (41), 19/19)

Barcelona, Hospital Mutua de Terrasa (hem-onco), T Marti (4 (4), 0/4)

Barcelona, Hospital General “Vall d'Hebron”, CIC 527, A Julia Font, J Zuazu (24 (27), 6/18)

Barcelona, Hospital Universitario Germans Trias i Pujol, CIC 613, J Ribera (29 (32), 8/21)

Barcelona, Hospital Sant Joan de Deu, CIC 668, J Estella Aguado (12 (18), 0/12)

Barcelona, Hospital Duran i Reynals (Hem), Institut Catala d'Oncologia, CIC 759, C Ferra, J Berlanga, A Fernàndez (31 (33), 13/18)

Barcelona, Inst Hemat Torre Vilana, Cen Medico Teknon, CIC 777, P Vivancos (inactive)

Barcelona, Instituto de Oncologia Corachan, D Alfonso-Modolell (0 (0), 0/0)

Caceres, Hospital San Pedro de Alcantara, M Luz Amigo Lozano (16 (19), 0/16)

Cadiz, Hospital del SAS de Jérez (hem), CIC 612, A Leon (29 (35), 9/20)

Cadiz, Hospital Universitario ‘Puerta del Mar’ (hem), CIC 679, J Gil (15 (15), 0/15)

Canary Isles, Las Palmas, Hospital Insular (hem), CIC 335, J Gonzalez-San Miguel (10 (12), 0/12)

Canary Isles, Las Palmas, Hospital Materno-Infantil (haem, onco), J Lodos Rojas, A Molinés (2 (2), 0/2)

Canary Isles, Las Palmas, Hospital Universitario de Gran Canaria ‘Dr Negrin’, T Molero, R Mataix, C Campo, S Jiménez (15 (18), 9/6)

Canary Isles, Teneriffe, Hospital Universitario de Canarias, L Hernandez Nieto, MT Hernandez Garcia (15 (15), 0/15)

Canary Isles, Teneriffe, University Hospital, P Rios Rull (11 (11), 0/11)

Castellon de La Plana, Hospital General de Castellon (haem), R Garcia-Boyero (8 (8), 0/8)

Cordoba, Hospital Reina Sofia (hem), CIC 238, A Torres Gomez (38 (40), 25/13)

Cordoba, Hospital de la Cruz Roja de Cordoba (haem), J-M Garcia-Castellano*

Cruces-Barakaldo, Hospital de Cruces (hem), CIC 393, I Zuazua-Verde, F Floristan (35 (36), 0/35)

Galdakao, Hospital de Galdakao, Hem, CIC 975, J Ojanguren, K Atutxa (9 (11), 0/9)

Granada, Hospital Virgen de la Nieves (hem), CIC 559, JM de Pablos Gallego (32 (36), 10/22)

Jaen, Hospital Cuidad de Jaen (haem), A Alcalam*

La Coruna, Complexo Hospitalario Juan Canalejo, CIC 361, FJ Batlle, C Ramirez, P Torres, R Varela (39 (43), 5/34)

Lérida, Hospital Arnan de Villanova, J Macia (11 (11), 0/11)

Lugo, Hospital Xeral-Calde, M Gonzales-Lopez (8 (8), 0/8)

Madrid, Hospital de la Princesa (hem), CIC 236, JM Fernández Rañada, A Figuera, A Alegre (60 (60), 32/28)

Madrid, Hospital Doce de Octubre, CIC 382, JJ Lahuerta (hem), H Cortés Funes (onco), J Lopez Perez (peds) (71 (75), 4/67)

Madrid, Hospital Ramon y Cajal (ads), CIC 615, J Odriozola, J Pérez de Oteyza, J Lopez, J Garcia Larana (42 (42), 19/23)

Madrid, Hospital Ramon y Cajal (peds), CIC 615, A Munoz Villa (3 (3), 0/3)

Madrid, Clinica Puerta de Hierro (hem), CIC 728, MN Fernandez (33 (42), 23/10)

Madrid, Hospital Nino Jesus (peds), CIC 732, MA Diaz (36 (42), 14/22)

Madrid, Hospital Universitario San Carlos (hem), CIC 733, J Diaz Mediavilla, L Llorente, R Martinez (35 (35), 0/35)

Madrid, Hospital General La Paz (ads), CIC 734, F Hernandez Navarro, M Canales (36 (39), 7/29)

Madrid, Hospital La Paz Infantil (hem, onco), CIC 734, A Martinez-Rubio, A Sastre (12 (15), 8/4)

Madrid, Unidad de TMO-ONC 4, Hospital Gregorio Maranon, CIC 819, JL Diez Martin (39 (42), 14/25)

Madrid, Clinica Moncloa (hem), JM Fernandez-Ranada, A Escudero (9 (10), 0/9)

Madrid, Clinica Ruber, JM Fernandez-Ranada, A Escudero (17 (17), 0/17)

Madrid, Hospital Ruber Internacional (onco), P Aramburo (0 (0), 0/0)

Madrid, Hospital Universitario de Getafe (hem), F Oña Compan, N Somolinos (5 (5), 0/5)

Madrid, Fundacion Jimenez Diaz (hem, onco), CIC 309, J Tomas, C Paniagua, F Lobo (20 (21), 6/14)

Madrid, Hospital Militar Gomez Ulla, F Sancho-Cuesta, S Enrech-Frances (0 (0), 0/0)

Malaga, Hospital Regional (hem), CIC 576, M Gonzalez, M Pascual (28 (29), 9/19)

Murcia, Hospital Univ “Virgen de la Arrixaca”, CIC 323, A Morales-Lazaro, MJ Majado-Martinez (6 (6), 0/6)

Murcia, Hospital Morales Meseguer, CIC 735, JM Moraleda Jimenez, V Vicente-Garcia, I Heras ((30 (37), 7/23)

Orense, Hospital Cristal-Pinor (hem), J-L Sastre-Moral (12 (13), 0/12)

Oviedo, Hospital Covadonga (hem), CIC 642, D Carrera Fernandez (34 (40), 6/28)

Palma de Mallorca, Hospital Son Dureta (hem), CIC 722, J Besalduch, M Canaro (27 (28), 9/18)

Palma de Mallorca, Policlinica Miramar, J Besalduch, A Sampol (2 (2), 0/2)

Pamplona, Hospital Provincial de Navarra (hem), CIC 577, E Pérez Equiza, MJ Uriz Pascual, J Gastearena (16 (16), 0/16)

Pamplona, Clinica Universitaria de Navarra, CIC 737, J Rifon (25 (29), 4/21)

Pontevedra, Hospital Montecelo (onco), CIC 549, M Constela (3 (3), 0/3)

Salamanca, Hospital Clinico (hem), CIC 727, D Caballero (73 (88), 25/48)

San Sebastian, Hospital Nostra Senora de Aranzazu, CIC 598, R Lasa, J Marin, D Martinez (35 (46), 1/34)

Santander, Hospital Universitario M de Valdecilla (hem), CIC 242, A Iriondo, E Conde (59 (68), 22/37)

Santiago de Compostela, Hospital Xeral de Galicia (hem), CIC 570, JL Bello (20 (20), 8/12)

Sevilla, Hospital Universitario Virgen del Rocio, CIC 769, JM Rodriguez Fernandez (62 (62), 26/36)

Tarragona, Hospital de Tarragona Joan XXlll (hem), A Llorente Cabrera (10 (10), 0/10)

Valencia, Hospital Clinico Universitario (hem, onco), CIC 282, J Garcia-Conde, CSolano (29 (30), 9/20)

Valencia, Hospital Infantil La Fe (peds, onco), CIC 653, V Castel, A Verdeguer, JM Fernandez (22 (26), 9/13)

Valencia, Hospital Universitario La Fe (hem), CIC 663, MA Sanz, GF Sanz (79 (97), 34/45)

Valencia, Hospital Doctor Peset (hem), P Ribas Garcia (7 (7), 0/7)

Valencia, Instituto Valenciano de Oncologia, I Picón (5 (5), 0/5)

Valladolid, Hospital Rio Hortega, CIC 611, J Garcia Frade (16 (19), 0/16)

Vigo, Hospital Xeral-Cies, A Martinez-Dalmau (20 (23), 2/18)

Zaragoza, Clinico Universitario Lozano Blesa (hem), CIC 531, M Gutierrez, J Moreno, L Palomera (15 (16), 0/15)

Zaragoza, Clinico Universitario Lozano Blesa (onco), A Tres, J Mayordomo (7 (7), 0/7)

Zaragoza, Hospital Miguel Servet (hem+onco) M Giralt, G Pérez-Lugmus, D Rubio-Félix, A Anton (27 (27), 3/24)

Sweden (9 teams; 485 (542), 149/336)

Goteborg, CHECT (ads+peds), CIC 289, M Brune, A Fasth, (101 (122), 32/68)

Huddinge, University Hospital (hem, onco), CIC 212, P Ljungman (91 (102), 56/35)

Linköping, University Hospital (hem), CIC 740, G Juliusson (47 (48), 14/33)

Lund, University Hospital (hem), CIC 283, AN Bekassy, S Lenhoff (72 (81), 15/57)

Malmö, University Hospital, I Turesson, T Ahlgren (7 (7), 0/7)

Örebro, University Hospital (hem, onco), CIC 738, U Tidefelt (10 (14), 0/10)

Stockholm, Karolinska Hospital (hem), CIC 626, M Björkholm (41 (41), 0/41)

Umea, Norrland University Hospital, CIC 731, A Wahlin, V Lazarevic, J Lindh, B Markevärn (43 (48), 7/36)

Uppsala, University Hospital (ads+peds), CIC 266, I Hassan, G Oberg (73 (79), 25/48)

Switzerland (10 teams; 354 (465), 114/240)

Aarau, Kantonsspital (hem, onco), CIC 316, M Wernli, M Bargetzi (30 (41), 0/30)

Basel, Kantonsspital (hem, onco), CIC 202, A Gratwohl, T Kühne, R Herrmann (63 (84), 50/13)

Bellinzona, Ospedale San Giovanni (hem, onco), CIC 829, F Cavalli, M Ghielmini L Leoncini (16 (20), 0/16)

Bern, Inselspital (ads, peds, hem, onco), CIC 221, K Leibundgut, C Zwicky, M Fey (54 (88), 0/54)

Geneva, Hôpital Cantonal Universitaire (hem, onco), CIC 261, B Chapuis, Y Chalandon, P Wacker (26 (29), 26/0)

Lausanne, CHUV (hem, onco), CIC 820, M Schapira, T Kovacsovics, S Leyvraz, N Ketterer (65 (78), 0/65)

St Gallen (hem, onco), Kantonsspital, CIC 324, U Hess (13 (14), 0/13)

Zurich, University Hospital (ads, hem, onco), CIC 208, U Schanz, J Halter, Ch Taverna (64 (86), 23/41)

Zurich, University Hospital (peds, hem, onco), CIC 334, R Seger (20 (20), 15/5)

Zurich, Klinik Im Park (onco), CIC 700, J Gmür, U Breitenstein (3 (5), 0/3)

Tunisia (1 team; 67 (74), 34/33)

Tunis, Centre National de Greffe de Moelle Osseuse, CIC 183, B Othman (67 (74), 34/33)

Turkey (26 teams; 493 (517), 203/290)

Ankara-Sihhiye, Hacettepe University (hem), CIC 168, H Goker, O Ozcebe, I Haznedaroglu, S Dundar (12 (12), 8/4)

Ankara-Besevler, Gazi University (hem), CIC 169, R Haznedar (8 (8), 2/6)

Ankara, Hacettepe University, Institute of Oncology, CIC 292, E Kansu, Y Koc, E Ozdemir (38 (40), 8/30)

Ankara-Etlik, GATA BMT Center, CIC 372, F Arpaci, A Özet, C Beyan, A Ural (49 (53), 16/33)

Ankara, Ihsan Dogramaci Childrens Hospital, ATuncer, D Uckan (16 (16), 16/0)

Ankara, University School of Medicine Ibni Sina Hospital (hem), CIC 617, G Gürman (60 (68), 32/28)

Ankara, University of Ankara (peds), CIC 620, E Unal (17 (17), 12/5)

Ankara, Numune Education and Research Hospital, CIC 691, M Ayli (60 (62), 37/23)

Antalya, Akdeniz University Hospital (peds), CIC 618, MA Yesilipek, V Hazar, O Yegin (19 (19), 14/5)

Antalya, Akdeniz University Hospital (hem), CIC 685, L Undar (16 (17), 3/13)

Aydin, Adnan Menderes University Medical Faculty (hem), CIC 187, Z Bolaman (3 (3), 1/2)

Balcali (Adana), Cukurova University Hospital (peds, hem, onco), CIC 821:1, A Tanyeli (0 (0), 0/0)

Balcali (Adana), Cukurova University Hospital (ads, onco), CIC 821:2, B Sahin (14 (14), 0/14)

Bornova-Izmir, Ege University Medical Faculty (peds), CIC 621, S Kansoy (7 (7), 3/4)

Bornova-Izmir, Ege University Medical Faculty (ads, hem), CIC 628, S Cagirgan (55 (58), 10/45)

Eskisehir, Osmangazi University, CIC 686, Z Güblas (8 (11), 2/6)

Istanbul, Maltepe Medical Faculty, CIC 210, K Ozerkan, A Tamkan*

Istanbul, Marmara University (hem), Altunizade, CIC 714, T Akoglu (7 (7), 1/6)

Istanbul, University of Istanbul, CIC 760, S Kalayoglu-Besisik (21 (21), 8/13)

Istanbul, Cerrahpasa Medical School, CIC 761, B Ferhanoglu, T Soysal, Z Baslar (26 (27), 12/14)

Istanbul, Tip Fakultesi (peds, hem, onco), CIC 762, G Gedikoglu (5 (5), 4/1)

Istanbul, GATA Haydarpasa Egitim Hast (hem, onco), CIC 687, A Öztürk*

Istanbul, Institute of Oncology, CIC 689, H Onat, M Basaran*

Izmir, Dokuz Eylul University (onco), CIC 688, U Yilmaz (8 (8), 0/8)

Kayseri, Erciyes University Hospital (hem, onco), CIC 627, A Unal, M Cetin (32 (32), 10/22)

Trabzon, Karadeniz Technical University (hem), CIC 170, E Ovali (12 (12), 4/8)

Ukraine: (2 teams; 31 (36), 1/30)

Kiev, Kiev City BMT Center, CIC 176, E Karamanescht, V Khomenko, I Korenkova, S Borodkin (31 (36), 1/30)

Kiev, Kiev Regional Oncologic Hospital (peds, hem, onco), CIC 177, S Donska, O Ryzhak*

United Kingdom (54 teams; 2209 (2380), 785/1424)

Aberdeen, The Royal Infirmary (hem), CIC 344, DJ Culligan (17 (18), 0/17)

Bangor, Gwynedd Hospital (hem, onco), CIC 736, M Gilleece (10 (11), 0/10)

Bath, Royal United Hospital (hem), CIC 619, C Knechtli (16 (16), 0/16)

Belfast, Belfast City Hospital (hem), CIC 268, F Jones, TCM Morris, P Abram (35 (35), 6/29)

Birmingham, Heartlands Hospital (hem), CIC 284, DW Milligan (55 (62), 10/45)

Birmingham, Queen Elizabeth Hospital (hem), CIC 387, C Craddock, P Mahendra (101 (105), 37/64)

Birmingham, The Birmingham Childrens Hospital (hem), CIC 781, PJ Darbyshire (41 (42), 24/17)

Bournemouth, Royal Bournemouth Hospital (hem), Poole Hospital, Dorset Cancer Centre and Salisbury District Hospital, CIC 765, S Killick, J Cullis (13 (13), 0/13)

Bristol, Royal Hospital for Children (allo, ads, peds), CIC 386:1, JM Cornish, D Marks (56 (72), 49/7)

Bristol, Avon Haematology Unit (auto), CIC 386:2, R Evely, J Bird (27 (29), 0/27)

Cambridge, Addenbrooke's Hospital (hem), CIC 566, C Crawley, RE Marcus, J Craig, H Balsdon, T Chapman (56 (59), 16/40)

Cardiff, University Hospital of Wales (hem), CIC 303, KMO Wilson, AK Burnett, JA Whittaker, CH Poynton (50 (55), 13/39)

Cheltenham, Cheltenham General Hospital, E Blundell (19 (19), 0/19)

Coventry, University Hospital & Warwickshire NHS Trust, J Mills (15 (15), 0/15)

Dundee, Ninewells Hospital (hem), CIC 719, D Meiklejohn (4 (4), 0/4)

Edinburgh, Western General Hospital, (hem) CIC 228, JMDavies, PRE Johnson, MJ Mackie, PH Roddie, P Shepherd (34 (34), 4/30)

Exeter, Royal Devon and Exeter Hospital (hem), CIC 571, M Joyner (16 (16), 0/16)

Glasgow, Royal Infirmary, CIC 244, A Parker, IG McQuaker (63 (65), 35/28)

Glasgow, The Western Infirmary (hem), CIC 325, T Fitzsimons (18 (20), 0/18)

Glasgow, Royal Hospital for Sick Children (hem), CIC 707, B Gibson (11 (11), 7/4)

Leeds, St James's University Hospital & The General Infirmary, CIC 254, S Kinsey, G Cook (121 (128), 24/97)

Leicester, Royal Infirmary (hem), CIC 713, AE Hunter (42 (45), 16/26)

Liverpool, Royal Liverpool University Hospital (hem), CIC 501, RE Clark, A Pettitt (42 (47), 17/25)

Liverpool, Alder Hay, CIC 773, M Caswell (9 (9), 3/6)

London, Hammersmith & Charing Cross Hospital, CIC 205, J Apperley, E Olavarria, E Kanfer, A Rahemtulla, R Szydlo (130 (145), 51/79)

London, Royal Free Hospital (hem), CIC 216, M Potter (51 (51), 30/21)

London, Royal Marsden Hospital (hem), CIC 218, M Ethell, J Mehta (128 (154), 23/105)

London, University College Hospital (onco), CIC 224, J Whelan (11 (13), 0/11)

London, University College Hospital (hem), CIC 224, S MacKinnon (142 (147), 51/91)

London, Great Ormond Street Hospital, CIC 243, P Veys (51 (52), 45/6)

London, The London Clinic (hem), CIC 263, PJ Gravett (20 (21), 10/10)

London, St George's Hospital (hem), CIC 539, J Marsh, S Ball, EC Gordon-Smith (23 (25), 13/10)

London, Guy's Hospital (hem), CIC 721, S Schey (35 (35), 8/27)

London, King's College (hem), CIC 763, A Pagliuca, GJ Mufti (116 (127), 75/41)

London, St Bartholomew's, CIC 768 and the Royal London Hospital, J Cavenagh, S Agrawal, T Lister (64 (68), 11/53)

Manchester, Royal Children's Hospital, CIC 521, AM Will (14 (19), 13/1)

Manchester, The Royal Infirmary, JA Yin (45 (49), 31/14)

Manchester, Christie Hospital (hem), CIC 780, E Liakopoulou (60 (65), 19/41)

Manchester, Trafford General Hospital, PA Carrington (3 (3), 0/3)

Newcastle upon Tyne, Royal Victoria Infirmary, CIC 276, GHJackson, SJ Proctor, P Taylor, A Cant, R Skinner (89 (97), 37/52)

Norwich, Norfolk and Norwich Hospital (hem), CIC 391, J Parker, G Turner (5 (5), 0/5)

Nottingham, City Hospital, CIC 717, N Russell, JL Byrne, AP Haynes, A McMillan (102 (111), 46/56)

Oxford, John Radcliffe Hospital (hem, onco), Headington and Wycombe General, CIC 255, TJ Littlewood, C Bunch, C Mitchell, CHatton, G Hall, J Wainscoat (47 (47), 17/30)

Plymouth, Derriford Hospital, CIC 823, MD Hamon (41 (42), 14/27)

Salford, Hope Hospital, PA Carrington (4 (4), 0/4)

Sheffield, Royal Hallamshire Hospital – J Snowdon, Weston Park Hospital – L Evans,

Rotherham General Hospital – H Barker and the Children's Hospital – A Vora, CIC 778:1/2/3/5 (54 (61), 15/39)

Somerset, Taunton and Somerset Hospital SA Johnson, S Bolam (13 (13), 0/13)

Southhampton, CRC Wessex, CIC 704, K Orchard, A Duncombe, J Kohler (53 (57), 15/38)

Stoke-on-Trent, North Staffordshire Royal Infirmary (hem), CIC 394, R Chasty (8 (9), 0/8)

Sunderland, The Sunderland Royal Hospital, PJ Carey (2 (2), 0/2)

Swansea, Singleton Hospital, Skett, S Al Ismail (11 (12), 0/11)

Swindon, Great Western Hospital (Hem), CIC 608, NE Blesing, A Gray, S Green, A Koster (4 (4), 0/4)

Wakefield, The Mid Yorkshire Hospitals NHS Trust, Pinderfields Hospital, CIC 254, M C Galvin, P Hillmen (12 (12), 0/12)

Yugoslavia (Serbia and Montenegro) (4 teams; 26 (27), 10/16)

Belgrade, Mother and Child Health Institute, CIC 358, D Vujic (2 (2), 0/2)

Belgrade, Clinical Centre of Serbia (hem), CIC 373, M Colovic, A Bogdanovic (0 (0), 0/0)

Belgrade, Military Medical Academy (hem), CIC 582, M Malesevic (24 (25), 10/14)

Novi Sad, Institute of Internal Diseases, Clinical Centre of Novi Sad (hem), CIC 655, D Pejin*

*No report

Totals 21028 (25207), 7091/13937

January 2005

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Gratwohl, A., Baldomero, H., Schmid, O. et al. Change in stem cell source for hematopoietic stem cell transplantation (HSCT) in Europe: a report of the EBMT activity survey 2003. Bone Marrow Transplant 36, 575–590 (2005). https://doi.org/10.1038/sj.bmt.1705104

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