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Why does immunity to parasites take so long to develop?

Abstract

To ensure successful transmission and establish chronic infection, parasites must evade the host's immune system and delay the development of immunity. Maria Yazdanbakhsh and David Sacks discuss how this might be achieved.

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Correspondence to David L. Sacks.

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The authors declare no competing financial interests.

Supplementary information

Supplementary information S1 (Table)

Global impact of parasitic diseases', and current control measures (PDF 125 kb)

Supplementary information S2 (Figure)

Evading immune elimination. (PDF 525 kb)

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Yazdanbakhsh, M., Sacks, D. Why does immunity to parasites take so long to develop?. Nat Rev Immunol 10, 80–81 (2010). https://doi.org/10.1038/nri2673

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