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Inflammation and cancer: the long reach of Ras

Nature Medicine volume 11, pages 20–21 (2005)Cite this article

For decades cancer biologists have thought of oncogenes in terms of their ability to prompt tumor growth and survival, acting within the cancer cell. That viewpoint is now changing to take into account data showing that oncogenes influence inflammation. Insights now emerge from work on Ras and the proinflammatory mediator interleukin-8, produced by tumor-infiltrating immune cells.

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Figure 1: Ras reaches out.

Ann Thomson

Figure 2: Beyond the grave.

Ann Thomson

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  1. Department of Pharmacology at the University of California, San Diego School of Medicine, La Jolla, 92093, California, USA

    Michael Karin

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  1. Michael Karin
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Karin, M. Inflammation and cancer: the long reach of Ras. Nat Med 11, 20–21 (2005). https://doi.org/10.1038/nm0105-20

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