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Unrelated peripheral blood stem cell transplantation for Fanconi anemia

Bone Marrow Transplantation volume 19, pages 299–300 (1997)Cite this article

Abstract

The Brazilian unrelated bone marrow donor program began in 1993 and an unrelated matched donor was found for a Fanconi anemia patient without a sibling match. An 11-year-old female recipient received FTBI (6.0 Gy) and cyclophosphamide (40 mg/kg) as conditioning. The 41-year-old female unrelated donor received G-CSF at 5 μ g/kg × 5 days, and on day 6 and 7 post-mobilization, peripheral blood stem cells were harvested. Engraftment was seen on day 19 post-BMT and she remains alive and well on day 191+. This case supports the potential role of harvesting G-CSF-stimulated PBSC for unrelated bone marrow transplantation.

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Authors and Affiliations

  1. Department of Hematology, Fundação Pró-Sangue/Hemocentro de São Paulo, Brazil

    C Massumoto, JR Moraes, ME Moraes, MCA Macedo, R Medeiros, D Chamone & F Dulley

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  1. C Massumoto
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  2. JR Moraes
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  3. ME Moraes
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  4. MCA Macedo
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  5. R Medeiros
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  6. D Chamone
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  7. F Dulley
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Massumoto, C., Moraes, J., Moraes, M. et al. Unrelated peripheral blood stem cell transplantation for Fanconi anemia. Bone Marrow Transplant 19, 299–300 (1997). https://doi.org/10.1038/sj.bmt.1700654

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  • DOI: https://doi.org/10.1038/sj.bmt.1700654

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