The structure of beef heart cytochrome c oxidase has been determined. The structural information provides new insights into the mechanism of electron transfer-driven proton translocation. It does not explain why the eukaryotic form of the enzyme is so complex, with 13 different subunits.
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Capaldi, R. The complexity of a respiratory complex. Nat Struct Mol Biol 3, 570–574 (1996). https://doi.org/10.1038/nsb0796-570
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DOI: https://doi.org/10.1038/nsb0796-570