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Engineering of plasminogen activator inhibitor-1 to reduce the rate of latency transition

Mutational studies of a serine proteinase inhibitor (serpin) reveal determinants of its structural rearrangements.

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Tucker, H., Mottonen, J., Goldsmith, E. et al. Engineering of plasminogen activator inhibitor-1 to reduce the rate of latency transition. Nat Struct Mol Biol 2, 442–445 (1995). https://doi.org/10.1038/nsb0695-442

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