Recent clinical studies with bardoxolone methyl have demonstrated improvements in the glomerular filtration rate of diabetic patients with chronic kidney disease (CKD). Although its mechanism of action is uncertain, the persisting effects of bardoxolone methyl in this challenging group of patients are a source of optimism for the management of CKD.
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M. C. Thomas has received speakers bureau honoraria from Abbott. M. E. Cooper has worked as a consultant for Abbott.
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Thomas, M., Cooper, M. Bardoxolone improves kidney function in type 2 diabetes. Nat Rev Nephrol 7, 552–553 (2011). https://doi.org/10.1038/nrneph.2011.114
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DOI: https://doi.org/10.1038/nrneph.2011.114
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