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Long-distance signaling via presynaptic glutamate transporters

Glutamate transporters have long been thought to help terminate the synaptic response through neurotransmitter binding and reuptake, but a new report in this issue identifies a role for their anionic current in information transmission in the retina.

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Figure 1: Bipolar cells communicate with each other via glutamate spillover.

Lori Vaskalis

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Wadiche, J., von Gersdorff, H. Long-distance signaling via presynaptic glutamate transporters. Nat Neurosci 9, 1352–1353 (2006). https://doi.org/10.1038/nn1106-1352

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