Glutamate transporters have long been thought to help terminate the synaptic response through neurotransmitter binding and reuptake, but a new report in this issue identifies a role for their anionic current in information transmission in the retina.
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References
Fairman, W.A., Vandenberg, R.J., Arriza, J.L., Kavanaugh, M.P. & Amara, S.G. Nature 375, 599–603 (1995).
Wadiche, J.I., Amara, S.G. & Kavanaugh, M.P. Neuron 15, 721–728 (1995).
Arriza, J.L., Eliasof, S., Kavanaugh, M.P. & Amara, S.G. Proc. Natl. Acad. Sci. USA 94, 4155–4160 (1997).
Brasnjo, G. & Otis, T.S. Neuron 31, 607–616 (2001).
Wadiche, J.I. & Jahr, C.E. Nat. Neurosci. 8, 1329–1334 (2005).
Sarantis, M., Everett, K. & Attwell, D. Nature 332, 451–453 (1988).
Picaud, S.A., Larsson, H.P., Grant, G.B., Lecar, H. & Werblin, F.S. J. Neurophysiol. 74, 1760–1771 (1995).
Hasegawa, J., Obara, T., Tanaka, K. & Tachibana, M. Neuron 50, 63–74 (2006).
Veruki, M.L., Morkve, S.H. & Harveit, E. Nat. Neurosci. 9, 1388–1396 (2006).
Fremeau, R.T. Jr., Voglmaier, S., Seal, R.P. & Edwards, R.H. Trends Neurosci. 27, 98–103 (2004).
Palmer, M.J., Taschenberger, H., Hull, C., Tremere, L. & von Gersdorff, H. J. Neurosci. 23, 4831–4841 (2003).
Wersinger, E. et al. J. Physiol. (Lond.) advance online publication 14 September 2006 (doi:10.1113/jphysiol.2006.118281).
Zenisek, D., Davila, V., Wan, L. & Almers, W. J. Neurosci. 23, 2538–2548 (2003).
Pow, D.V. & Barnett, N.L. Cell Tissue Res. 297, 57–66 (1999).
Ingram, S.L., Prasad, B.M. & Amara, S.G. Nat. Neurosci. 5, 971–978 (2002).
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Wadiche, J., von Gersdorff, H. Long-distance signaling via presynaptic glutamate transporters. Nat Neurosci 9, 1352–1353 (2006). https://doi.org/10.1038/nn1106-1352
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DOI: https://doi.org/10.1038/nn1106-1352
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