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The yin and yang of cortical layer 1

Abstract

Distinct populations of layer 1 inhibitory neurons inhibit or disinhibit layer 5 pyramidal cells. A massive patch-clamp recording effort, tapping up to eight cells simultaneously, maps their influences on the cortical network.

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Figure 1: Inhibitory neurons and their interaction with the active properties of pyramidal cells.

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Correspondence to Matthew E Larkum.

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Larkum, M. The yin and yang of cortical layer 1. Nat Neurosci 16, 114–115 (2013). https://doi.org/10.1038/nn.3317

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