Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Hydrogels

Wet or let die

Nature Materials volume 3, pages 7–8 (2004)Cite this article

Proteins are like fish in that they need water to survive — without it they lose vitality and become unable to carry out their functions. A new hydrogel material for protein microarray chips keeps the proteins wet and lively.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: The correct environment for proteins.

References

  1. Kiyonaka, S. et al. Nature Mater. 3, 58–64 (2004).

    Article  CAS  Google Scholar 

  2. Zhang, S., Holmes, T., Lockshin, C. & Rich, A. Proc. Natl Acad. Sci. USA 90, 3334–3338 (1993).

    Article  CAS  Google Scholar 

  3. Aggeli, A. et al. Nature 386, 259–262 (1997).

    Article  CAS  Google Scholar 

  4. Petka, W.A., Harden, J.L., McGrath, K.P., Wirtz, D. & Tirrell, D.A. Science 281, 389–392 (1998).

    Article  CAS  Google Scholar 

  5. Lee, J., Macosko, C.W. & Urry, D.W. Biomacromolecules 2, 170–179 (2001).

    Article  CAS  Google Scholar 

  6. Hartgerink, J.D., Beniash, E. & Stupp, S.I. Science 294, 1684–1688 (2001).

    Article  CAS  Google Scholar 

  7. Nowak, A.P. et al. Nature 417, 424–428 (2002).

    Article  CAS  Google Scholar 

  8. Schneider, J.P. et al. J. Am. Chem. Soc. 124, 15030–15037 (2002).

    Article  CAS  Google Scholar 

  9. Jin, H.J. & Kaplan, D.L. Nature 424, 1057–1061 (2003).

    Article  CAS  Google Scholar 

  10. Zhang, S. Nature Biotech. 21, 1171–1178 (2003).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Center for Biomedical Engineering and the Center for Bits and Atoms, Massachusetts Institute of Technology, Cambridge, 02139, Massachusetts, USA

    Shuguang Zhang

Authors
  1. Shuguang Zhang
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Zhang, S. Wet or let die. Nature Mater 3, 7–8 (2004). https://doi.org/10.1038/nmat1047

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nmat1047

This article is cited by

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing