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Inhibition by Interferon Preparations of a Solid Malignant Tumour and Pulmonary Metastases in Mice

Nature New Biology volume 236, pages 78–79 (1972)Cite this article

Abstract

WE have reported the efficacy of exogenous interferon preparations in inhibiting the development of several virus-induced leukaemias of mice. These are the Friend1,2 and Rauscher leukaemias3 as well as the spontaneously appearing lymphoid leukaemia of AKR mice4. Comparable interferon preparations also inhibited the growth of transplantable ascitic tumours (of viral and non-viral origin) and markedly increased the survival of tumour inoculated mice5,6. We thought it would be interesting to determine the effect of interferon on the growth of a solid metastasizing tumour.

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Authors and Affiliations

  1. Department of Viral Oncology, Institut de Recherches sur le Cancer, Villejuif, 94

    ION GRESSER & CHANTAL BOURALI-MAURY

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  1. ION GRESSER
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  2. CHANTAL BOURALI-MAURY
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GRESSER, I., BOURALI-MAURY, C. Inhibition by Interferon Preparations of a Solid Malignant Tumour and Pulmonary Metastases in Mice. Nature New Biology 236, 78–79 (1972). https://doi.org/10.1038/newbio236078a0

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