Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letters to Editor
  • Published:

Evidence for a Complex between Myosin and ADP in Relaxed Muscle Fibres

Abstract

TAYLOR and his co-workers have shown that myosin, when mixed with its substrate ATP, rapidly forms a stoichiometric complex in which the terminal phosphate bond of the ATP is already broken1; this complex is relatively stable and lasts for nearly all of the time between successive ATP hydrolyses2. The aim of the present work was to find out whether such a complex is formed in relaxed muscle.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

References

  1. Lymn, R., and Taylor, E. W., Biochemistry, 9, 2975 (1970).

    Article  CAS  Google Scholar 

  2. Taylor, E. W., Lymn, R., and Moll, G., Biochemistry, 9, 2984 (1970).

    Article  CAS  Google Scholar 

  3. Jewell, B. R., and Ruegg, J. C., Proc. Roy. Soc., B, 164, 428 (1966).

  4. Marsh, B. B., Biophys. Biochim. Acta, 33, 357 (1959).

    Article  Google Scholar 

  5. Kominz, D. R., Biochemistry, 9, 1792 (1970).

    Article  CAS  Google Scholar 

  6. Huxley, H. E., The Cell (edit. by Brachet, J., and Mirsky, A. E.), 4, 419 (Academic Press, London and.New York, 1960).

    Google Scholar 

  7. Lowey, S., Slayter, H., Weeds, A., and Baker, H., J. Mol. Biol., 42, 1 (1969).

    Article  CAS  Google Scholar 

  8. Godfrey, J. E., and Harrington, W. F., Biochemistry, 9, 886 (1970).

    Article  CAS  Google Scholar 

  9. Noda, L., J. Biol. Chem., 232, 237 (1958).

    CAS  PubMed  Google Scholar 

  10. Carslaw, H. S., and Jaeger, J. C., Conduction of Heat in Solids, 199 (Oxford University Press, 1959).

  11. Szent-Gyorgyi, A. G., and Prior, G., J. Mol. Biol., 15, 515 (1966).

    Article  CAS  Google Scholar 

  12. Ebashi, S., and Endo, M., Prog. Biophys., 18, 123 (1968).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

MARSTON, S., TREGEAR, R. Evidence for a Complex between Myosin and ADP in Relaxed Muscle Fibres. Nature New Biology 235, 23–24 (1972). https://doi.org/10.1038/newbio235023a0

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1038/newbio235023a0

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing