Cytoskeletal attachment to the cell cortex is crucial for mechanical and signalling events at the plasma membrane. The adenomatous polyposis coli (APC) protein, as well as β-catenin in a complex with cytoplasmic dynein, is implicated in mediating such cortical attachment.
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Allan, V., Näthke, I. Catch and pull a microtubule: getting a grasp on the cortex. Nat Cell Biol 3, E226–E228 (2001). https://doi.org/10.1038/ncb1001-e226
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DOI: https://doi.org/10.1038/ncb1001-e226
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