Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Short Communication
  • Published:

Childhood overweight or obesity increases the risk of IIH recurrence fivefold

Abstract

Overweight and obesity are less closely associated with idiopathic intracranial hypertension (IIH) in young children than in post-pubescent children and adults. We examined the hypothesis that being overweight or obese (body mass index (BMI) 85th percentile) in children is a risk factor for IIH recurrence. A total of 43 children with IIH who were followed up for an average of 9±3.4 years were evaluated in a retrospective case–control series. The rate of IIH recurrence was compared between children of healthy weight and children presenting with overweight or obesity, using survival curve analysis. The overall risk for long-term IIH recurrence in children is ~20%. Following weight stratification, the risk for IIH recurrence in our cohort was fivefold higher in children with a BMI 85th percentile (57%) than in healthy weight children (11%; log-rank test P=0.04). Pediatricians may consider counseling families that weight control may be a means of decreasing the risk of IIH recurrence.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1

Similar content being viewed by others

References

  1. Szewka AJ, Bruce BB, Newman NJ, Biousse V . Pediatric idiopathic intracranial hypertension and extreme childhood obesity: a comment on visual outcomes. J Pediatr 2012; 161: 972.

    Article  Google Scholar 

  2. Biousse V, Bruce BB, Newman NJ . Update on the pathophysiology and management of idiopathic intracranial hypertension. J Neurol Neurosurg Psychiatry 2012; 83: 488–494.

    Article  Google Scholar 

  3. Tibussek D, Distelmaier F, von Kries R, Mayatepek E . Pseudotumor cerebri in childhood and adolescence — results of a Germany-wide ESPED-survey. Klin Padiatr 2013; 225: 81–85.

    Article  CAS  Google Scholar 

  4. Brara SM, Koebnick C, Porter AH, Langer-Gould A . Pediatric idiopathic intracranial hypertension and extreme childhood obesity. J Pediatr 2012; 161: 602–607.

    Article  Google Scholar 

  5. Balcer LJ, Liu GT, Forman S, Pun K, Volpe NJ, Galetta SL et al. Idiopathic intracranial hypertension: relation of age and obesity in children. Neurology 1999; 52: 870–872.

    Article  CAS  Google Scholar 

  6. Babikian P, Corbett J, Bell W . Idiopathic intracranial hypertension in children: the Iowa experience. J Child Neurol 1994; 9: 144–149.

    Article  CAS  Google Scholar 

  7. Pollak L, Zohar E, Glovinsky Y, Huna-Baron R . Reevaluation of presentation and course of idiopathic intracranial hypertension - a large cohort comprehensive study. Acta Neurol Scand 2013; 127: 406–412.

    Article  CAS  Google Scholar 

  8. Tibussek D, Schneider DT, Vandemeulebroecke N, Turowski B, Messing-Juenger M, Willems PH et al. Clinical spectrum of the pseudotumor cerebri complex in children. Childs Nerv Syst 2010; 26: 313–321.

    Article  Google Scholar 

  9. Friedman DI, Jacobson DM . Diagnostic criteria for idiopathic intracranial hypertension. Neurology 2002; 59: 1492–1495.

    Article  Google Scholar 

  10. Center for Disease Control and Prevention. BMI percentile calculator for child and teen. English version. At: http://apps.nccd.cdc.gov/dnpabmi/.

  11. Soiberman U, Stolovitch C, Balcer LJ, Regenbogen M, Constantini S, Kesler A . Idiopathic intracranial hypertension in children: visual outcome and risk of recurrence. Childs Nerv Syst 2011; 27: 1913–1918.

    Article  Google Scholar 

  12. Honorat R, Marchandot J, Tison C, Cances C, Chaix Y . Treatment and prognosis of idiopathic intracranial hypertension in children. Retrospective study (1995–2009) and literature review. Arch Pediatr 2011; 18: 1139–1147.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to H Stiebel-Kalish.

Ethics declarations

Competing interests

The authors declare no conflict of interest.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Stiebel-Kalish, H., Serov, I., Sella, R. et al. Childhood overweight or obesity increases the risk of IIH recurrence fivefold. Int J Obes 38, 1475–1477 (2014). https://doi.org/10.1038/ijo.2014.44

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/ijo.2014.44

Keywords

This article is cited by

Search

Quick links