Abstract
Adults of Drosophila hydei react differently towards ethanol and propan-2-ol treatment. Ethanol concentration rises progressively in ethanol fed flies and the acetaldehyde produced is quickly metabolised. Alcohol dehydrogenase and aldo-keto reductase activities rise considerably after 48 hours of ethanol treatment decreasing progressively afterwards. In propan-2-ol treated flies propan-2-ol concentration rises in the first 72 hours after ingestion and the acetone produced tends to accumulate in the flies but eventually it is excreted. Alcohol dehydrogenase activity decreases markedly whereas aldo-keto reductase activity is induced by three-fold after 72 hours. Cycloheximide treatment inhibits the recovery of alcohol dehydrogenase activity of propan-2-ol treated flies when transferred to normal medium.
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Gonzàlez-Duarte, R., Atrian, S. Metabolic response to alcohol ingestion in Drosophila hydei. Heredity 56, 123–128 (1986). https://doi.org/10.1038/hdy.1986.17
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DOI: https://doi.org/10.1038/hdy.1986.17
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