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Chemical modification of DNA polymerase phosphoprotein from avian myeloblastosis virus

Nature volume 266, pages 27–31 (1977)Cite this article

Abstract

Fractionation of purified avian myeloblastosis virus DNA polymerase, after phosphorylation in vitro, revealed the presence of a small acidic protein, a phosphate acceptor polypeptide with high specific activity. Its presence in the phosphorylated form with the polymerase resulted in as much as a 10-fold increase in the rate of DNA synthesis. Its presence in the dephosphorylated form with the polymerase had no effect in the rate of DNA synthesis.

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Author notes

  1. Chris M. Tsiapalis

    Present address: Meloy Laboratories Inc., 6715 Electronic Drive, Springfield, Virginia, 22151

Authors and Affiliations

  1. Life Sciences Research Laboratories, 1509½ 49th Street South, St Petersburg, Florida, 33707

    Chris M. Tsiapalis

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  1. Chris M. Tsiapalis
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Tsiapalis, C. Chemical modification of DNA polymerase phosphoprotein from avian myeloblastosis virus. Nature 266, 27–31 (1977). https://doi.org/10.1038/266027a0

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