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Reduction of possible hazards in the preparation of recombinant plasmid DNA

Abstract

THE preparation of plasmid DNA requires the collection of plasmid-containing bacteria, usually by centrifugation of liquid cultures. This step is a potential source of laboratory contamination, especially when large volumes, requiring continuous flow centrifugation, are processed.

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WEISSMANN, C., BOLL, W. Reduction of possible hazards in the preparation of recombinant plasmid DNA. Nature 261, 428–429 (1976). https://doi.org/10.1038/261428a0

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