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Quantitative Variation of 6-Phosphogluconate Dehydrogenase in an African Population

Abstract

IN a previous report we described the relatively high frequency of the electrophoretic phenotype 6-PGD AB of 6-phosphogluconate dehydrogenase (EC 1.1.1.44; 6-PGD) in the local African population1. Our further experience confirms this: 6-PGD AB has been found in 115 of 500 Africans (23.0 per cent) compared with 23 of 300 Whites (7.6 per cent). The very rare phenotype 6-PGD B has been found in 12 of 500 Africans (2.4 per cent), but has not yet been found in the local White population.

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References

  1. Gordon, H., Keraan, M. M., and Vooijs, M., Nature, 214, 466 (1967).

    Article  ADS  CAS  Google Scholar 

  2. Carter, N. D., Fildes, R. A., Fitch, L. I., and Parr, C. W., Acta Genet. (Basel), 18, 109 (1968).

    CAS  Google Scholar 

  3. King, J., Practical Clinical Enzymology, 99 (Van Nostrand, 1965).

    Google Scholar 

  4. Bishop, C., J. Lab. Clin. Med., 68, 149 (1966).

    CAS  PubMed  Google Scholar 

  5. Brewer, G. J., and Dern, R. J., Amer. J. Human Genet., 16, 472 (1964).

    CAS  Google Scholar 

  6. Parr, C. W., and Fitch, L. I., Ann. Human Genet., 30, 339 (1967).

    Article  CAS  Google Scholar 

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GORDON, H., KERAAN, M., WOODBURNE, V. et al. Quantitative Variation of 6-Phosphogluconate Dehydrogenase in an African Population. Nature 221, 96–97 (1969). https://doi.org/10.1038/221096a0

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