Abstract
Albumin penetration into animal cells is stimulated by basic polyamino acids and DEAE-dextran, and increases with the size of the polymers. This dependence on size suggests that multiple attachment of a macromolecule to the membrane is necessary for biological function.
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References
Ryser, H. J.-P., Lab. Invest., 12, 1009 (1963).
Ryser, H. J.-P., Aub, J. C., and Caulfield, J. B., J. Cell Biol., 15, 437 (1962).
Caulfield, J. B., Lab. Invest., 12, 1018 (1963).
Ryser, H. J.-P., Caulfield, J. B., and Aub, J. C., J. Cell Biol., 14, 255 (1962).
Ryser, H. J.-P, Science, 150, 501 (1965).
Katchalsky, A., Danon, D., and Nevo, A., Biochim. Biophys. Acta, 33, 120 (1959).
Applequist, J., and Doty, P., in Polyamino Acids, Polypeptides and Proteins (edit. by Stahmann, M. A.), 161 (University of Wisconsin Press, Madison, 1962).
Gill, T. J., and Omenn, G. S., J. Amer. Chem. Soc., 87, 4188 (1965).
Zubay, G., and Doty, P., J. Mol. Biol., 1, 1 (1959). Bradbury, E. M., and Crane-Robinson, C., in The Nucleohistone (edit. by Bonner, J., and T'so, P.), 117 (Holden Day, San Francisco, 1964).
Wallach, D. F. H., and Zahler, P. H., Proc. US Nat. Acad. Sci., 56, 1829 (1966).
Lenard, J., and Singer, S. J., Proc. US Nat. Acad. Sci., 56, 1829 (1966).
Weiss, L., and Mayhew, E., J. Cell Physiol., 68, 345 (1967).
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RYSER, HP. A Membrane Effect of Basic Polymers dependent on Molecular Size. Nature 215, 934–936 (1967). https://doi.org/10.1038/215934a0
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DOI: https://doi.org/10.1038/215934a0
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