Abstract
STREPTOZOTOCIN, an antibiotic isolated from Streptomyces achromogenes1, has been found to be diabetogenic in rats and dogs2. Our previous investigation3 described the development of glycogen nephrosis in rats treated with streptozotocin. The present communication is a report on an unusual type of renal and extrarenal neoplasia encountered in rats given a single dose of streptozotocin and placed under observation from 8 to 16 months after the injection.
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References
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ARISON, R., FEUDALE, E. Induction of Renal Tumour by Streptozotocin in Rats. Nature 214, 1254–1255 (1967). https://doi.org/10.1038/2141254a0
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DOI: https://doi.org/10.1038/2141254a0
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