Abstract
INTEREST in the possible role of histone as an inhibitor of DNA dependent RNA synthesis has increased recently1,2. During an investigation of the synthesis of microgram quantities of RNA by wheat nuclei isolated by the method of Johnson et al.3 it was observed that the addition of 10 mmolar ascorbate to the medium in which the nuclei were incubated resulted in a large increase in the amount of RNA synthesized (Table 1). No stimulation of DNA synthesis by ascorbate was ever observed even under conditions of active DNA synthesis.
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PRICE, C. Ascorbate Stimulation of RNA Synthesis. Nature 212, 1481 (1966). https://doi.org/10.1038/2121481a0
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DOI: https://doi.org/10.1038/2121481a0
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