This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Brookes, P., and Lawley, P. D., Biochem. J., 80, 496 (1961).
Ross, W. C. J., Adv. Cancer Res., 1, 397 (Academic Press, New York, 1953).
Crathorn, A. R., and Roberts, J. J., Prog. Biochem. Pharmacol., 1, 320 (1965).
Walker, I. G., Science, 151, 99 (1966).
Setlow, R. B., and Carrier, W. L., Proc. U.S. Nat. Acad. Sci., 51, 226 (1964).
Boyce, R. P., and Howard-Flanders, P., Proc. U.S. Nat. Acad. Sci., 51, 293 (1964).
Lawley, P. D., and Brookes, P., Nature, 206, 480 (1965).
Brewer, jun., H. B., Comstock, J. P., and Aronow, L., Biochem. Pharmacol., 8, 281 (1961).
Levis, A. G., Danieli, G. A., and Piccinni, E., Nature, 207, 608 (1965).
Nias, A. H. W., Gilbert, C. W., Lajtha, L. G., and Lange, C. S., Intern. J. Radiat. Biol., 9, 275 (1965).
Haynes, R. H., Photochem. Photobiol., 3, 429 (1964).
Kirby, K. S., Biochem. J., 96, 266 (1965).
Kidson, C., Kirby, K. S., and Ralph, R., J. Mol. Biol., 7, 312 (1963).
Layde, J. P., and Baserga, R., Brit. J. Cancer, 18, 150 (1964).
Brookes, P., and Lawley, P. D., Biochem. J., 89, 127 (1963).
Rosenberg, B. M., and Cavalieri, L. F., Proc. U.S. Nat. Acad. Sci., 51, 826 (1964).
Crathorn, A. R., and Roberts, J. J. (unpublished results).
Painter, R. B., and Rasmussen, R. E., Nature, 201, 162 (1964).
Brent, T. P., Butler, J. A. V., and Crathorn, A. R., Nature, 210, 393 (1966).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
CRATHORN, A., ROBERTS, J. Mechanism of the Cytotoxic Action of Alkylating Agents in Mammalian Cells and Evidence for the Removal of Alkylated Groups from Deoxyribonucleic Acid. Nature 211, 150–153 (1966). https://doi.org/10.1038/211150a0
Issue Date:
DOI: https://doi.org/10.1038/211150a0
This article is cited by
-
Late Cardiac Complications of Sulfur Mustard Poisoning in 38 Iranian Veterans
Cardiovascular Toxicology (2019)
-
Bromodeoxyuridine: a diagnostic tool in biology and medicine, Part III. Proliferation in normal, injured and diseased tissue, growth factors, differentiation, DNA replication sites andin situ hybridization
The Histochemical Journal (1996)
-
Resistance to cytostatic drugs at the cellular level
Cancer Chemotherapy and Pharmacology (1992)
-
Positive correlation between decreased cellular uptake, NADPH-glutathione reductase activity and adriamycin resistance in Ehrlich ascites tumor lines
Archives of Toxicology (1987)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.