Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Article
  • Published:

Impairment of Sympathetic Transmission by Botulinum Toxin

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

References

  1. Burn, J. H., and Rand, M. J., Nature, 184, 163 (1959).

    Article  ADS  Google Scholar 

  2. MacIntosh, F. C., Birks, R. I., and Sastry, P. B., Nature, 178, 1181 (1956).

    Article  ADS  CAS  PubMed  Google Scholar 

  3. Reitzel, N. L., and Long, J. P., Arch. Int. Pharmacodyn., 119, 20 (1959).

    CAS  PubMed  Google Scholar 

  4. Wilson, H., and Long, J. P., Arch. Int. Pharmacodyn., 120, 343 (1959).

    CAS  PubMed  Google Scholar 

  5. Chang, V., and Rand, M. J., Brit. J. Pharmacol., 15, 588 (1960).

    CAS  PubMed  PubMed Central  Google Scholar 

  6. Wong, K. C., and Long, J. P., J. Pharmacol. Exp. Therap., 133, 211 (1961).

    CAS  Google Scholar 

  7. Bowman, W. C., and Rand, M. J., Brit. J. Pharmacol., 17, 176 (1961).

    CAS  PubMed  PubMed Central  Google Scholar 

  8. Leaders, F. E., and Long, J. P., J. Pharmacol. Exp. Therap., 137, 206 (1962).

    CAS  Google Scholar 

  9. Armaly, M. F., Whinery, R. L., and Long, J. P., Arch. Int. Pharmacodyn., 145, 89 (1963).

    CAS  PubMed  Google Scholar 

  10. Lewartowski, B., and Bielecki, K., J. Pharmacol. Exp. Therap., 142, 24 (1963).

    CAS  Google Scholar 

  11. Long, J. P., and Highgenboten, C. L., Arch. Int. Pharmacodyn., 149, 385 (1964).

    CAS  PubMed  Google Scholar 

  12. Hukovič, S., Rand, M. J., and Vanov, S., Brit. J. Pharmacol., 24, 178 (1965).

    PubMed  PubMed Central  Google Scholar 

  13. Evans, E. R., and Wilson, H., Brit. J. Pharmacol., 22, 441 (1964).

    CAS  PubMed  PubMed Central  Google Scholar 

  14. Gardiner, J. E., J. Physiol., 138, 13P (1957).

    Google Scholar 

  15. Gardiner, J. E., Biochem. J., 81, 297 (1961).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  16. Farah, A. E., in Schueler, F. W., Int. Rev. Neurobiol., 2, 77 (1960).

    Article  Google Scholar 

  17. Birks, R. I., in MacIntosh, F. C., Fed. Proc., 20, 562 (1961).

    Google Scholar 

  18. MacIntosh, F. C., Fed. Proc., 20, 562 (1961).

    CAS  PubMed  Google Scholar 

  19. Bentley, G. A., and Sabine, J. R., Brit. J. Pharmacol., 21, 190 (1963).

    CAS  PubMed  PubMed Central  Google Scholar 

  20. Birmingham, A. T., and Wilson, A. B., Brit. J. Pharmacol., 21, 569 (1963).

    CAS  PubMed  PubMed Central  Google Scholar 

  21. Rand, M. J., and Ridehaglh, A., J. Pharm. Pharmacol., 17, 144 (1965).

    Article  CAS  PubMed  Google Scholar 

  22. Brandon, K. W., and Rand, M. J., J. Physiol., 157, 18 (1961).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  23. Gardiner, J. E., and Thompson, J. W., Nature, 191, 86 (1961).

    Article  ADS  CAS  PubMed  Google Scholar 

  24. Bentley, G. A., Brit. J. Pharmacol., 19, 85 (1962).

    CAS  PubMed  PubMed Central  Google Scholar 

  25. Bevan, J. A., and Su, C., Brit. J. Pharmacol., 22, 176 (1964).

    CAS  PubMed  PubMed Central  Google Scholar 

  26. Burn, J. H., Rand, M. J., and Wien, R., Brit. J. Pharmacol., 20, 83 (1963).

    CAS  PubMed  PubMed Central  Google Scholar 

  27. Burn, J. H., and Rand, M. J., Brit. J. Pharmacol., 15, 56 (1960).

    CAS  PubMed  PubMed Central  Google Scholar 

  28. Boyd, H., Chang, V., and Rand, M. J., Brit. J. Pharmacol., 15, 525 (1960).

    CAS  PubMed  PubMed Central  Google Scholar 

  29. Bernard, P. J., and de Schaepdryver, A. F., Arch. Int. Pharmacodyn., 148 301 (1964).

    CAS  PubMed  Google Scholar 

  30. Bowman, W. C., Callingham, B. A., and Cuthbert, A. W., Brit. J. Pharmacol., 22, 558 (1964).

    CAS  PubMed  PubMed Central  Google Scholar 

  31. Burn, J. H., and Weetman, D. F., Brit. J. Pharmacol., 20, 74 (1963).

    CAS  PubMed  PubMed Central  Google Scholar 

  32. Burn, J. H., and Gibbons, W. R., Brit. J. Pharmacol., 22, 527 (1964).

    CAS  PubMed  PubMed Central  Google Scholar 

  33. Feldberg, W., and Vartiainen, A., J. Physiol., 83, 103 (1935).

    Article  Google Scholar 

  34. Brown, G. L., Dale, H. H., and Feldberg, W., J. Physiol., 87, 394 (1936).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  35. Brücke, F. T., Klin. Wschr., 14/i, 7 (1935).

    Article  Google Scholar 

  36. Hellmann, K., J. Physiol., 169, 603 (1963).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  37. Green, A. F., Advances in Pharmacology, 1, 162 (1962).

    Google Scholar 

  38. Dixit, B. N., Gulati, O. D., and Gokhale, S. D., Brit. J. Pharmacol., 17, 372 (1961).

    CAS  PubMed  PubMed Central  Google Scholar 

  39. Koelle, G. B., J. Pharm. Pharmacol., 14, 65 (1962).

    Article  CAS  PubMed  Google Scholar 

  40. Burn, J. H., and Rand, M. J., Ann. Rev. Pharmacol. (in the press).

  41. Whaler, B. C., Biochem. Pharmacol., 12, Supp., 261 (1963).

    Google Scholar 

  42. Burgen, A. S. V., Dickens, F., and Zatman, L. J., J. Physiol., 109, 10 (1949).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  43. Wright, G. P., Pharmacol. Rev., 7, 413 (1955).

    CAS  PubMed  Google Scholar 

  44. Brooks, V. B., J. Physiol., 123, 501 (1954).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  45. Brooks, V. B., J. Physiol., 134, 264 (1956).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  46. Ambache, N., J. Physiol., 108, 127 (1949).

    Article  PubMed  PubMed Central  Google Scholar 

  47. Ambache, N., Brit. J. Pharmacol., 6, 51 (1951).

    CAS  PubMed  PubMed Central  Google Scholar 

  48. Ambache, N., J. Physiol., 113, 1 (1951).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  49. Harry, J., Brit. J. Pharmacol., 19, 42 (1962).

    CAS  PubMed  PubMed Central  Google Scholar 

  50. Hukovič, S., Brit. J. Pharmacol., 16, 188 (1961).

    PubMed  PubMed Central  Google Scholar 

  51. Finkleman, B., J. Physiol., 70, 145 (1930).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  52. Coon, J. M., and Rothman, S., J. Pharmacol. Exp. Therap., 68, 301 (1941).

    Google Scholar 

  53. Burn, J. H., and Rand, M. J., J. Physiol., 150, 295 (1960).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  54. Whaler, B. C., (unpublished observations).

  55. Sjöstrand, N. O., Acta Physiol. Scand., 54, 306 (1962).

    Article  PubMed  Google Scholar 

  56. Ohlin, P., and Strömblad, B. C. R., Brit. J. Pharmacol., 20, 299 (1963).

    CAS  PubMed  PubMed Central  Google Scholar 

  57. Ferry, C. B., J. Physiol., 166, 16P (1963).

    Google Scholar 

  58. Kuriyama, H., J. Physiol., 169, 213 (1963).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  59. Hilton, S. M., and Lewis, G. P., J. Physiol., 128, 235 (1955).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  60. Burn, J. H., and Rand, M. J., Advances in Pharmacology, 1, 1 (1962).

    Article  CAS  Google Scholar 

  61. Ambache, N., Pharmacol. Rev., 7, 467 (1955).

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

RAND, M., WHALER, B. Impairment of Sympathetic Transmission by Botulinum Toxin. Nature 206, 588–591 (1965). https://doi.org/10.1038/206588a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/206588a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing