Abstract
MANY types of alkylating mutagens had been applied to barley before the mutagenicity of sulphonates was observed. Ethyl methanesulphonate (EMS) was the first tested and is now widely used in mutation research. The related compounds methyl methanesulphonate (MMS) (refs. 1, 3, 4), n-propyl methanesulphonate (nPMS) (refs. 1–3), isopropyl methanesulphonate (isoPMS) (ref. 3) and others also have been shown to be mutagenic on barley.
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References
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Ehrenberg, L., Gustafsson, Å., and Lundqvist, U., Hereditas, 47, 243 (1961).
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Minocha, J. L., and Arnason, T. J., Nature, 196, 499 (1962).
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FROESE-GERTZEN, E., NILAN, R., KONZAK, C. et al. Effects of n-Butyl Methanesulphonate and Related Mutagens on Barley. Nature 200, 714–715 (1963). https://doi.org/10.1038/200714a0
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DOI: https://doi.org/10.1038/200714a0
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