Abstract
THE distribution of nucleic acids and proteins within the cell varies from organ to organ. Tissues rich in ribonucleic acid (RNA) are particularly active in protein synthesis, thus indicating a close association between protein synthesis and RNA concentration1–3. Work from several laboratories now clearly shows that RNA is one of the essential components for protein synthesis2,4. Because of the relatively high concentration of RNA5–7 and protein8, and the absence of enzyme systems to hydrolyse adenosine triphosphate (ATP) and guanosine triphosphate (GTP) in the ocular lens9,10, this organ may offer certain advantages for the investigation of protein biosynthesis as compared with a more complex organ such as the liver.
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DEVI, A., LERMAN, S. & SARKAR, N. Incorporation of Amino-Acids into Protein and Ribonucleic Acid of the Lens of the Rat ; Effect of Heavy Metals. Nature 190, 1193–1195 (1961). https://doi.org/10.1038/1901193a0
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DOI: https://doi.org/10.1038/1901193a0
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