Abstract
RECENTLY, Mundry and Gierer1 used nitrous acid to produce mutants of tobacco mosaic virus by chemical alteration of its ribonucleic acid, as demonstrated by Schuster and Schramm2. This communication deals with the mutagenic effects of nitrous acid on living cells of the bacterial species Escherichia coli and Salmonella typhimurium, the genetic substance of which is deoxyribonucleic acid.
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References
Mundry, K.-W., and Gierer, A., Z. Vererbungslehre, 89, 614 (1958); Nature, 182, 145 (1958).
Schuster, H., and Schramm, G., Z. Naturforsch., 13 b, 698 (1958).
Lederberg, J., and Lederberg, E. H., J. Bact., 63, 399 (1952).
Kaudewitz, F., Vielmetter, W., and Friedrich-Freksa, H., Z. Naturforsch., 13 b, 793 (1959).
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KAUDEWITZ, F. Production of Bacterial Mutants with Nitrous Acid. Nature 183, 1829–1830 (1959). https://doi.org/10.1038/1831829a0
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DOI: https://doi.org/10.1038/1831829a0
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