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The Experimental Transmission of Cutaneous Leishmaniasis to Man from Phlebotomus papatasii

Abstract

SERGENT, ED. et Et., Parrot, L., Donatien, H., and Béguet, M. (C.R. Acad. Sci., vol. 173, No. 21, pp. 1030–1032), first successfully transmitted cutaneous Leishmaniasis to man from sandflies. Their experiment consisted of dividing a batch of 559 sandflies into 23 batches, crushing the sandflies in saline, and inoculating scarified points on the arms of volunteers. The sandflies were caught in Biskra, an endemic centre of cutaneous Leishmaniasis, and the experiment was performed in Algiers, where locally acquired cases of the disease are unknown. One experiment (from a batch of 7 specimens of Phlebotomus papatasii) was successful, Leishman-Donovan bodies being found from a papule which appeared 2 months and 24 days after the experiment.

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ADLER, S., THEODOR, O. The Experimental Transmission of Cutaneous Leishmaniasis to Man from Phlebotomus papatasii. Nature 116, 314–315 (1925). https://doi.org/10.1038/116314b0

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