Entwicklungspsychopathologie der ADHS
Abstract
Galt die ADHS vor einigen Jahren noch als eine Erkrankung des Kindes- und Jugendalters, so versteht man heute darunter ein Störungsbild über die Lebensspanne. Mit Beginn im Vorschulalter divergieren die Symptome in Abhängigkeit des Alters. Daraus lässt sich ein Modell ableiten, welches diese Veränderungen (Komorbiditäten, Alltagsbeeinträchtigungen) auf der Zeitachse dokumentiert und mit den jeweils gültigen diagnostischen Kriterien in Verbindung bringt. Ausgehend von einer genetischen Prädisposition und einer neurobiologischen Dysregulation sind Faktoren festzustellen, die über die Lebensspanne andauern, sich altersspezifisch verändern oder nur für einen bestimmten Entwicklungsabschnitt gültig sind. Es wird deutlich, dass das Vorschulalter und der Übergang in das Erwachsenenalter die Phasen darstellen, in denen sich die meisten qualitativen Veränderungen feststellen lassen. Dies hat Implikationen für die klinische Praxis, indem diese Veränderungen zu Zwecken der Prävention, des diagnostischen Prozesses und der Therapieplanung herangezogen werden können und somit sowohl dem Anwender eine Hilfestellung bieten, aber auch als Ausgangspunkt für weitere Studien herangezogen werden können.
Attention deficit/hyperactivity disorder (ADHD), formerly regarded as a typical disorder of childhood, has recently been conceptualized as a disorder persisting across the lifespan. With an onset during preschool age, symptoms vary according to developmental phase investigated. From the perspective of developmental psychopathology, a model is introduced that comprises both the stability and variability of ADHD symptoms and of concurrent comorbidity across the lifespan. Based on a genetic vulnerability and associated neuropsychological dysfunction, developmental factors shape the quality and intensity of symptoms across childhood, adolescence and adulthood. These age-dependent differences in clinical expression have major implications for clinical assessment and intervention as well as for future research strategies.
Literatur
2008). ADHD from a socio-economic perspective. Acta Paediatrica, 92, 239–245.
(2005). Attention-deficit/hyperactivity disorder: A selective overview. Biological Psychiatry, 57, 1215–1220.
(2005). Attention-deficit hyperactivity disorder. The Lancet, 366, 237–248.
V. (2004). Gender effects on Attention-deficit/hyperactivity disorder in adults, revisited. Biological Psychiatry, 55, 692–700.
(2007). Reasons for substance use and vulnerability factors in patients with substance use disorder and anxiety or mood disorders. Addictive Behaviors, 32, 384–391.
(2008). Nature of anxiety comorbid with attention deficit hyperactivity disorder in children from a pediatric primary care setting. Psychiatry Research, 157, 201–209.
(2008). The association between attention deficit hyperactivity disorder in adolescence and smoking in adulthood. American Journal on Addictions, 17, 54–59.
(2007). Inattention as a key predictor of tobacco use in adolescence. Journal of Abnormal Psychology, 116, 249–259.
(2008). Cingulate-precuneus interactions: A new locus of dysfunction in adult attention-deficit/hyperactivity disorder. Biological Psychiatry, 63, 332–337.
(2007). Association between response inhibition and working memory in adult ADHD: A link to right frontal cortex pathology? Biological Psychiatry, 61, 1395–1401.
(2006). Response to cocaine, alone and in combination with methylphenidate, in cocaine abusers with ADHD. Drug and Alcohol Dependence, 82, 158–167.
M. (2005). Attention deficit hyperactivity disorder and borderline personality disorder. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 29, 865–877.
(2005). History of attention-deficit hyperactivity disorder symptoms and opioid dependence: A controlled study. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 29, 291–296.
(2005). Aufmerksamkeitsdefizit-/Hyperaktivitätsstörung (ADHS): Wie valide sind die Subtypen? Kindheit und Entwicklung, 14, 244–254.
(2007). Differentiating major depressive disorder in youths with attention deficit hyperactivity disorder. Journal of Affective Disorders, 102, 125–130.
(2006). Wirksamkeit verhaltenstherapeutischer Gruppenprogramme bei Kindern mit Aufmerksamkeitsdefizit- und Hyperaktivitätsstörungen (ADHS). Kindheit und Entwicklung, 15, 255–266.
(1998). Parent ratings of attention-deficit/hyperactivity-disorder: Factor structure, normative data and psychometric properties. Journal of Psychopathology and Behavioral Assessment, 20, 83–102.
(2006). Consultation-based academic interventions for children with ADHD: Effects on reading and mathematics achievement. Journal of Abnormal Child Psychology, 34, 633–646.
(2007). Integrating genetic, psychopharmacological and neuroimaging studies: A converging methods approach to understanding the neurobiology of ADHD. Developmental Review, 27, 374–395.
(2003). ADHS im Erwachsenenalter – Leitlinien auf der Basis eines Expertenkonsensus mit Unterstützung der DGPPN. Der Nervenarzt, 10, 939–946.
(2007). Prospective effects of attention-deficit/hyperactivity disorder, conduct disorder, and sex on adolescent substance use and abuse. Archives of General Psychiatry, 64, 1145–1152.
(2005). Diminished prefrontal brain function in adults with psychopathology in childhood related to attention deficit hyperactivity disorder. Psychiatry Research: Neuroimaging, 138, 157–169.
(2005). Molecular genetics of attention-deficit/hyperactivity disorder. Biological Psychiatry, 57, 1313–1323.
(2008). Cannabis use and adult ADHD symptoms. Drug and Alcohol Dependence, 95, 90–96.
(2007). Hyperactive children as young adults: Driving abilities, safe driving behavior, and adverse driving outcomes. Accident Analysis and Prevention, 39, 94–105.
(2002). History of childhood attention deficit/hyperactivity disorder symptoms and borderline personality disorder: A controlled study. Comprehensive Psychiatry, 43, 369–377.
(2008). Adolescent self-regulation as resilience: Resistance to antisocial behavior within the deviant peer context. Journal of Abnormal Child Psychology, 36, 273–284.
(1999). The extended version of the Strengths and Difficulties Questionnaire as a guide to child psychiatric caseness and consequent burden. Journal of Child Psychology and Psychiatry, 40, 791–801.
(2008). Attention deficit hyperactivity disorder in preschool children. Child and Adolescent Psychiatric Clinics of North America, 17, 347–366.
(2004). Aufmerksamkeitsdefizit-/Hyperaktivitätsstörungen. Kindheit und Entwicklung, 13, 131–136.
(2008). Personale, familiäre und soziale Schutzfaktoren und gesundheitsbezogene Lebensqualität chronisch kranker Kinder und Jugendlicher. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz, 51, 606–620.
(2007). Prenatal smoking exposure and psychiatric symptoms in adolescence. Acta Paediatrica, 96, 377–382.
(2007). Diagnostik und Therapie von Aufmerksamkeitsstörungen. Monatsschrift Kinderheilkunde, 155, 921–927.
(2001). ADHD in Swedish 3- to 7-year-old children. Journal of the American Academy of Child and Adolescent Psychiatry, 40, 1021–1028.
(2007). Clinical and psychoeducational profile of children with specific learning disability and co-occurring attention-deficit hyperactivity disorder. Indian Journal of Medical Sciences, 61, 639–647.
(2005). Patterns and predictors of attention-deficit/hyperactivity disorder persistence into adulthood: Results from the national comorbidity survey replication. Biological Psychiatry, 57, 1442–1451.
(2006). The dopamine transporter gene and the impulsivity phenotype in attention deficit hyperactivity disorder: A case-control association study in a Korean sample. Journal of Psychiatric Research, 40, 730–737.
(2004). Zum Konzept der Inhibition in der Psychopathologie. Zeitschrift für Klinische Psychologie, Psychiatrie und Psychotherapie, 52, 91–117.
(2007). Psychopathie im Kindesalter. Kindheit und Entwicklung, 16, 260–266.
(2007). Aufmerksamkeitsstörungen im Kindesalter. Kindheit und Entwicklung, 16, 7–15.
(2005). Predicting future antisocial personality disorder in males from a clinical assessment in childhood. Journal of Consulting and Clinical Psychology, 73, 389–399.
(2007). Academic and educational outcomes of children with ADHD. Ambulatory Pediatrics, 7, 82–90.
(2008). Childhood attention deficit hyperactivity disorder and the development of substance use disorders: Valid concern or exaggeration. Addictive Behaviors, 33, 451–463.
(2008). Genetics of attention deficit hyperactivity disorder. Child and Adolescent Psychiatric Clinics of North America, 17, 261–284.
V. (2007). Axis I and II comorbidity in adults with ADHD. Journal of Abnormal Psychology, 116, 519–528.
V. (2007). Prenatal smoking exposure and dopaminergic genotypes interact to cause a severe ADHD subtype. Biological Psychiatry, 61, 1320–1328.
(2006). Psychotherapie der Aufmerksamkeitsdefizit-/Hyperaktivitätsstörung (ADHS) im Erwachsenenalter. Zeitschrift für Psychiatrie, Psychologie und Psychotherapie, 54, 111–121.
(2008). Smoking during pregnancy and hyperactivity-inattention in the offspring-comparing results from three Nordic cohorts. International Journal of Epidemiology, doi:10.1093/ije/dym290.
(2007). Klinische Kinderneuropsychologie. Kindheit und Entwicklung, 16, 1–6.
(2006). Ressourcen – ein Grundbegriff der Entwicklungspsychologie und Entwicklungspsychopathologie? Kindheit und Entwicklung, 15, 118–127.
(2006). Association between amygdala hyperactivity to harsh faces and severity of social anxiety in generalized social phobia. Biological Psychiatry, 59, 424–429.
(2006). Differential diagnosis and comorbidity of attention-deficit/hyperactivity disorder (ADHD) and borderline personality disorder (BPD) in adults. European Archives of Psychiatry and Clinical Neuroscience, 256, 42–46.
(2008). Attention-deficit hyperactivity disorder as a potentially aggravating factor in borderline personality disorder. The British Journal of Psychiatry, 192, 118–123.
(2005). Behavior differences in drivers with attention deficit hyperactivity disorder: The driving behavior questionnaire. Accident Analysis and Prevention, 37, 996–1004.
(2008). A functional serotonin transporter promoter gene polymorphism increases ADHD symptoms in delinquents: Interaction with adverse childhood environment. Psychiatry Research, 158, 123–131.
(2006). Die Aufmerksamkeitsdefizit-/Hyperaktivitätsstörung (ADHS) im Erwachsenenalter. Zeitschrift für Psychiatrie, Psychologie und Psychotherapie, 54, 77–86.
(2004). Prevalence of attention deficit-/hyperactivity disorder (ADHD) and comorbid disorders in young male prison inmates. European Archives of Psychiatry and Clinical Neuroscience, 254, 365–371.
(2007). Die Prävalenz der Aufmerksamkeitsdefizit-/Hyperaktivitätsstörung (ADHS) bei Kindern und Jugendlichen in Deutschland. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz, 50, 827–835.
(2008). Persönlichkeitsstörungen im Kindes- und Jugendalter? Kindheit und Entwicklung, 17, 190–202.
(2006). Komorbidität der Aufmerksamkeitsdefizit-/Hyperaktivitätsstörung (ADHS) im Erwachsenenalter: Perspektiven für die Diagnostik mit dem Screeningverfahren BAS-E. Zeitschrift für Psychiatrie, Psychologie und Psychotherapie, 54, 123–132.
(2008). Homburger ADHS-Skalen für Erwachsene (HASE). Zeitschrift für Psychiatrie, Psychologie und Psychotherapie, 56, 155–159.
(2006). Neuropsychological functioning in people with ADHD across the lifespan. Clinical Psychology Review, 26, 466–485.
(2008). Effects of diagnostic comorbidity and dimensional symptoms of attention-deficit hyperactivity disorder in men with antisocial personality disorder. Australian and New Zealand Journal of Psychiatry, 42, 405–413.
(2008). «I have always felt different»: The experience of attention-deficit/hyperactivity disorder in childhood. Journal of Pediatric Nursing, 23, 49–57.
(2008). Subtype differences in adults with attention-deficit/hyperactivity disorder (ADHD) with regard to ADHD-symptoms, psychiatric comorbidity and psychosocial adjustment. European Psychiatry, 23, 142–149.
(2005). Anxiety disorders in an attention-deficit/hyperactivity disorder clinical sample. Arquivos de Neuro-Psiquiatria, 63, 407–409.
(2007). Further evidence of dopamine transporter dysregulation in ADHD: A controlled PET imaging study using altropane. Biological Psychiatry, 62, 1059–1061.
(2007). Attention-deficit/hyperactivity disorder: Diagnosis, lifespan, comorbidities, and neurobiology. Journal of Pediatric Psychology, 32, 631–642.
(2008). Investigation of the dopamine D5 receptor gene (DRD5) in adult attention deficit hyperactivity disorder. Neuroscience Letters, 432, 50–53.
(2006). Diagnostik der Aufmerksamkeitsdefizit-/Hyperaktivitätsstörung (ADHS) im Erwachsenenalter. Zeitschrift für Psychiatrie, Psychologie und Psychotherapie, 54, 87–98.
(2008). Reward anticipation and outcomes in adult males with attention-deficit/hyperactivity disorder. NeuroImage, 39, 966–972.
(2005). Social interpretation bias and generalized social phobia: The influence of developmental experiences. Behaviour Research and Therapy, 43, 759–777.
(2007). Meta-analysis of structural imaging findings in attention-deficit/hyperactivity disorder. Biological Psychiatry, 61, 1361–1369.
(2007). Brain dopamine transporter levels in treatment and drug naive adults with ADHD. NeuroImage, 34, 1182–1190.
(2000). Attention-deficit hyperactivity disorder in children, adolescents and adults. Oxford: Oxford University Press.
(2002). Psychiatric comorbidity and functioning in clinically referred preschool children and school-age youths with ADHD. Journal of the American Academy of Child and Adolescent Psychiatry, 41, 262–268.
(2003). Can adults with attention-deficit/hyperactivity disorder be distinguished from those with comorbid bipolar disorder? Findings from a sample of clinically referred adults. Biological Psychiatry, 54, 1–8.
(1999). Utility of behavior ratings by examiners during assessments of preschool children with attention-deficit/hyperactivity disorder. Journal of Abnormal Child Psychology, 27, 463–472.
(2006). Entwicklung und konfirmatorische Prüfung eines Rasch-skalierten Beurteilungsbogens für die Aufmerksamkeitsdefizit-/Hyperaktivitätsstörung (ADHS) im Grundschulalter. Kindheit und Entwicklung, 15, 170–181.
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