Abstract
Purpose: To determine the rate of ocular involvement in cutaneous leishmaniasis (CL). Methods: Nine hundred and eighty seven cutaneous leishmaniasis patients diagnosed and identified by clinical examination and parasitological methods in Harrankapi Health Centre between January 1996 and November 1997 were examined at the Harran University School of Medicine Eye Clinic, Sanliurfa, Turkey. Results: One thousand seven hundred and three CL lesions were identified in 987 patients (484 women and 503 men) with ages ranging from 0 to 78 years (mean ± SD 16.70 ± 13.47 years). A total of 33 lesions were located on the eyelid and in the periorbital region, making up 1.93% of all cutaneous lesions and 3.57% of facial lesions. In three cases with ocular involvement, blepharoconjunctivitis was identified, and in one case with ocular involvement, mechanical ptosis, lagophthalmos and blepharoconjunctivitis were identified. Conclusions: It was observed that the size of the lesions and their vicinity to the marginal free edge of the eyelid played an important role in the occurrence of ocular symptoms. It was concluded that many ocular findings could be missed because of the failure to conduct ophthalmological examination of CL cases with eyelid involvement, and hence, proper follow up and treatment may not be carried out.
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Koff AB, Rosen T. Treatment of cutaneous leismaniasis. J Am Acad Dermatol 1994; 31: 693-708.
Schnur LF, Chance ML, Ebert F, Thomas SC, Peters W. The biochemical and serological taxonomy of visceriazing Leishmania. Ann Trop Med Parasitol 1981; 75: 131-144.
Ferrry AP. Cutaneous leishmaniasis (Oriental sore) of the eyelid. Am J Ophthalmol 1977; 84: 349-354.
Kalter DC. Laboratory tests for the diagnosis and evaluation of leishmaniasis. Dermatol Clin 1994; 12: 37-50.
Glover AT. Eyelid infections. In: Albert DM, Jacobiec FA (eds), Principles and practice of ophthalmology. Philadelphia: W.B. Saunders, 1994: 1702-1712.
de Andrade C. Interstitial and ulcerous keratitis in leishmaniaisis. Arch Ophthalmol 1942; 27: 1193-1198.
Aksoy S, Amstrong MYK, Dortbudak Z, et al. The GAP Project in Southeastern Turkey: The potential for emergence of diseases. Emerging Infect Dis 1995; 1: 62-63.
Grevelink SA, Lerner EA. Leishmaniasis. J Am Acad Dermatol 1996; 34: 257-272.
Chong H. Oriental sore. A look at trends in and approaches to the treatment of leishmaniasis. Int J Dermatol 1986; 25: 615-623.
Tomkins A, Bryceson A. Ocular leishmaniasis and pentamidine diabetes. Trans Roy Soc Trop Med Hyg 1972; 66: 948-950.
Abboud IA, Ragab HAA, Hanna LS. Experimental ocular leishmaniasis. Br J Ophthalmol 1970; 54: 256-262.
Morgan G. Case of cutaneous leishmaniasis of the lid. Br J Ophthalmol 1965; 49: 542-545.
Cairns JE. Cutaneous leishmaniasis (Oriental sore). A case with corneal involvement. Br J Ophthalmol 1968; 52: 481-483.
O'Neill DPO, Deutsch J, Carmichael AJ, Taylor R. Eyelid leishmaniasis in a patient with neurogenic ptosis. Br J Ophthalmol 1991; 75: 506-507.
Nandy A, Addy M, Chowdhury AB. Leishmanial blepharo-conjunctivitis. Trop Geogr Med 1991; 43: 303-306.
Abdel-Hameed AA, Hassan MEA, Abdalla KM, el-Basra A, Ahmed BO. Two cases of ocular leishmaniasis. Trop Geogr Med 1991; 43: 91-93.
Chu FC, Rodrigues MM, Cogan DG, Neva FA. Leishmaniasis affecting the eyelids. Arch Ophthalmol 1983; 101: 84-91.
Satici A, Gurler B, Gurel MS, Aslan G, Oguz H. Mechanical ptosis and lagophtalmos in cutaneous leishmaniasis. Br J Ophthalmol 1998; 82: 975.
Farah FS. Cutaneous leishmaniasis. In: Freunfelder FT, Roy F (eds), Current ocular therapy 4. Philadelpia: W.B. Saunders, 1995: 120-121.
Guerra R. Leishmaniasis of the lid in Tuscany. Ophthalmologica 1974; 168: 193-196.
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Satici, A., Gurler, B., Aslan, G. et al. Ocular involvement in cutaneous leishmaniasis four cases with blepharoconjunctivitis. Eur J Epidemiol 19, 263–266 (2004). https://doi.org/10.1023/B:EJEP.0000020346.15800.d3
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DOI: https://doi.org/10.1023/B:EJEP.0000020346.15800.d3