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2,3-Dihydro-5,6-tetramethylenespiro(cyclohexane-2-thieno[2,3-d]pyrimidine)-4(1H)-thione. A Novel Synthetic Route and Crystalline Structure

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Abstract

Self-condensation of cyclohexylidenecyanothioacetamide gave 2,3-dihydro-5,6-tetramethylenespiro(cyclohexane-2-thieno[2,3-d]pyrimidine)-4(1H)-thione, the structure of which was proved by X-ray analysis. A mechanism is proposed for its formation and its alkylation has been studied.

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Authors and Affiliations

  1. Taras Shevchenko State Teaching University, Lugansk, 91011, Ukraine

    A. D. Dyachenko & V. D. Dyachenko

  2. Ukraine National Academy of Sciences, Institute of Organic Chemistry, Kiev, 02094

    E. B. Rusanov & A. N. Chernega

  3. V. N. Karazin National University, Kharkov, 61077, Ukraine

    S. M. Desenko

Authors
  1. A. D. Dyachenko
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  2. E. B. Rusanov
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  3. V. D. Dyachenko
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  4. A. N. Chernega
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  5. S. M. Desenko
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Dyachenko, A.D., Rusanov, E.B., Dyachenko, V.D. et al. 2,3-Dihydro-5,6-tetramethylenespiro(cyclohexane-2-thieno[2,3-d]pyrimidine)-4(1H)-thione. A Novel Synthetic Route and Crystalline Structure. Chemistry of Heterocyclic Compounds 39, 1369–1375 (2003). https://doi.org/10.1023/B:COHC.0000010655.77713.17

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  • DOI: https://doi.org/10.1023/B:COHC.0000010655.77713.17

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