Abstract
Components of the antioxidant defense system in placental tissues were studied in women with normal pregnancy and full-term delivery and women with spontaneous abortions at 28-36 weeks. In women with spontaneous abortions glutathione peroxidase activity in placental tissues increased and the content of SH compounds decreased, which led to exhaustion of the antioxidant defense system. Glutathione-S-transferase activity also decreased, which attests to impaired detoxifying function of the placenta.
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Prokopenko, V.M., Partsalis, G.K., Pavlova, N.G. et al. Glutathione-Dependent System of Antioxidant Defense in the Placenta in Preterm Delivery. Bulletin of Experimental Biology and Medicine 133, 442–443 (2002). https://doi.org/10.1023/A:1019845217485
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DOI: https://doi.org/10.1023/A:1019845217485