Abstract
Transketolase can be used for synthesis of chiral intermediates and carbohydrates. However the enzyme is strongly deactivated by the educts. This deactivation depends on the reactor employed. An enzyme membrane reactor allows the continuous production of L-erythrulose with high conversion and stable operational points. A productivity (space-time yield) of 45g L d was reached.
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Bongs, J., Hahn, D., Schörken, U. et al. Continuous production of erythrulose using transketolase in a membrane reactor. Biotechnology Letters 19, 213–216 (1997). https://doi.org/10.1023/A:1018341204341
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DOI: https://doi.org/10.1023/A:1018341204341