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New Measuring Method in Isothermal Titration Calorimetry Based on a Proportional-Integral Controlled System

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Abstract

This paper introduces a new measuring method in Isothermal Titration Calorimetry (ITC). This method, based on a proportional-integral control system, offers many important advantages when compared to the frequently used proportional control: higher signal-to-noise ratio, improved stability of baseline, increased static and dynamic sensitivity, similar or smaller time constants and calibration constant independent of the control parameters.

Here an experimental proof of this method is detailed and full theoretical foundation will be discussed in a next paper.

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References

  1. J. L. Macqueron, J. Ortín, G. Thomas and V. Torra, Thermochim. Acta, 67 (1983) 213

    Article  CAS  Google Scholar 

  2. J. Ortin, A. Ramos, V. Torra, J. Vińals, E. Margas and W. Zielcnkiewicz, Thermochim. Acta, 76 (1984) 325.

    Article  CAS  Google Scholar 

  3. J. Hatt, E. Margas and W. Zielenkiewicz, Thermochim. Acta, 64 (1983) 305.

    Article  CAS  Google Scholar 

  4. S. Tanaka, Thermochim. Acta, 25 (1978) 269.

    Article  CAS  Google Scholar 

  5. S. Tanaka, Thermochim. Acta, 156 (1989) 117.

    Article  CAS  Google Scholar 

  6. C. Rey, J.R. Rodríguez and V. Pérez-Villar, Thermochim. Acta, 61 (1983) 1.

    Article  CAS  Google Scholar 

  7. E. Cesari, V. Torra, J. L. Macqueron, R. Prost, J. P. Dubes and H. Tachoire, Thermochum. Acta, 53 (1982) 1.

    Article  CAS  Google Scholar 

  8. E. Cesari, V. Torra, J. L. Macqueron, R. Prost, J. P. Dubes and H. Tachoire, Thermochim. Acta, 53 (1982) 17.

    Article  CAS  Google Scholar 

  9. J. Ortin, V. Torra, J. Vińals and E. Cesari, Thermochim. Acta, 70 (1983) 113.

    Article  CAS  Google Scholar 

  10. E. Cesari, J. Ortín, P. Pascual, V. Torra, J. Vińals, J. L. Macqueron, J. P. Dubes and H. Tachoire, Thermochim. Acta, 48 (1981) 367.

    Article  CAS  Google Scholar 

  11. G. W. H. Höhne, Thermochim. Acta, 22 (1978) 347.

    Article  Google Scholar 

  12. J. R. Rodriguez, C. Rey, V. Pérez-Villar, V. Torra, J. Ortin and J. Vińals, Thermochim. Acta, 63 (1986) 331.

    Article  Google Scholar 

  13. E. Margas and W. Zielenkiewicz, Thermochim. Acta, 215 (1993) 9.

    Article  Google Scholar 

  14. B.C. Kuo, Digital Control Systems, 2nd De., Saunders College Publishing, U.S.A. (1992).

    Google Scholar 

  15. S. L. Randzio, Thermochim. Acta, 44 (1981) 1.

    Article  Google Scholar 

  16. R. Ambrosetti, N. Ceccanti and C. Festa, J. Phys. E: Sci. Instrum., 16 (1983) 265.

    Article  CAS  Google Scholar 

  17. O. López-Mayorga, P. L. Matco, J. Mira and M. Cortijo, J. Phys. E. Sci. Instrum., 17 (1984) 1231.

    Article  Google Scholar 

  18. E. Freire, O. López-Mayorga and M. Straume, Anal. Chem., 62 (1990) 950A.

    Article  CAS  Google Scholar 

  19. M. El-Harrous, S. J. Gill and A. Parody-Morreale, Meas. Sci. Technol., 5 (1994) 1065.

    Article  CAS  Google Scholar 

  20. M. L. McGlashan, Thermochim. Acta, 72 (1984) 55.

    Article  CAS  Google Scholar 

  21. I. Wadsö, Thermochim. Acta, 169 (1990) 151.

    Article  Google Scholar 

  22. L. D. Hansen and D. J. Eatough, Thermochim. Acta, 70 (1983) 257.

    Article  CAS  Google Scholar 

  23. H. Huemer, E. Platzer and K. Rehak, Thermochim. Acta, 231 (1994) 21.

    Article  CAS  Google Scholar 

  24. I. Wadsö, Thermochim. Acta, 96 (1985) 313.

    Article  Google Scholar 

  25. T. Wiseman, S. Williston, J. F. Brandts and L. Lin, Anal. Biochem., 179 (1989) 131.

    Article  CAS  Google Scholar 

  26. J. Reuquerol, Thermochim. Acta, 96 (1985) 377.

    Article  Google Scholar 

  27. J. Barthel, Thermometric Titrations, Ed. John Wiley & Sons, USA (1975).

    Google Scholar 

  28. J. R. Leigh, Applied Digital Control: Theory, Design and Implementation, 2nd Ed., Prentice Hall International, UK (1992).

    Google Scholar 

  29. A. Velázquez-Campoy, O. López-Mayorga and M. A. Cabrerizo-Vílchez, to be published.

  30. K. R. Löblich, Thermochim. Acta, 231 (1994) 7.

    Article  Google Scholar 

  31. J. P. Dubes, R. Kechavarz and H. Tachuire, Termochim. Acta, 79 (1984) 15.

    Article  CAS  Google Scholar 

  32. O. López-Mayorga, P. L. Mateo and M. Cortijo, J. Phys. E: Sci. Instrum., 20 (1987) 265.

    Article  Google Scholar 

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Authors and Affiliations

  1. Departamento de Física Aplicada, Facultad de Ciencias, Universidad de Granada, 18071, Granada

    A. Velázquez-Campoy

  2. Instituto de Biotecnología de la Universidad de Granada, Universidad de Granada, 18071, Granada, Spain

    O. López-Mayorga & M. A. Cabrerizo-Vílchez

Authors
  1. A. Velázquez-Campoy
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  2. O. López-Mayorga
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  3. M. A. Cabrerizo-Vílchez
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Velázquez-Campoy, A., López-Mayorga, O. & Cabrerizo-Vílchez, M.A. New Measuring Method in Isothermal Titration Calorimetry Based on a Proportional-Integral Controlled System. Journal of Thermal Analysis and Calorimetry 52, 881–894 (1998). https://doi.org/10.1023/A:1010195432522

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