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Recurrent Chondrosarcoma of the Cranial Base: A Durable Response to Ifosfamide-doxorubicin Chemotherapy

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Abstract

The case of a 46-year old woman with recurrent chondrosarcoma of the cranial base, refractory to neurosurgical intervention and external radiotherapy is reported. She received five cycles of systemic chemotherapy utilizing ifosfamide and doxorubicin which resulted in a durable clinical and radiographic response lasting 52+ months. A review of the management options for recurrent chondrosarcoma of the cranial base is also presented.

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Authors and Affiliations

  1. Kentuckiana Medical Oncology Associates, USA

    Renato V. La Rocca (Associate Professor of Medicine) & Thomas R. Baeker

  2. University of Louisville School of Medicine, Louisville, KY, USA

    Kelli Wickline Morgan

  3. Department of Medicine, University of Louisville School of Medicine, Louisville, KY, USA

    Kristie Paris

  4. Department of Radiation Oncology, J. Graham Brown Cancer Center, University of Louisville School of Medicine, Louisville, KY, USA

    Renato V. La Rocca (Associate Professor of Medicine)

  5. Commonwealth Hematology/Oncology, Danville, KY, USA

    Thomas R. Baeker

Authors
  1. Renato V. La Rocca
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  2. Kelli Wickline Morgan
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  3. Kristie Paris
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  4. Thomas R. Baeker
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La Rocca, R.V., Morgan, K.W., Paris, K. et al. Recurrent Chondrosarcoma of the Cranial Base: A Durable Response to Ifosfamide-doxorubicin Chemotherapy. J Neurooncol 41, 281–283 (1999). https://doi.org/10.1023/A:1006154904014

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  • DOI: https://doi.org/10.1023/A:1006154904014

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