Abstract
We tested probiotic preparations containingBifidobacterium, Enterococcus , or Lactobacillus to seeif they affect production of organic acids and ammoniaby mixed cecal bacteria. Four preparations (Bibalance, Neorakuton, Yakult Seichoyaku, or YakultSeichoyaku BL) were digested with HC and pancreatinbefore adding to batch cultures of 50% pig cecalcontents. Concentrations of organic acids and ammonia inthe culture were quantified. Two preparationsstimulated the net production of short-chain fatty acids(SCFA) during the first 8 hr of incubation. From 8 to 24hr of incubation, all preparations accelerated the net production of SCFA, succinic and lacticacids, and three preparations slowed the net productionof isovaleric acid and ammonia, all dose-dependently.The above results indicate that the preparations tested accelerated the breakdown ofhard-to-degrade carbohydrate(s) and, possibly thereby,decreased the breakdown of proteinous materials orincreased bacterial cell body synthesis in a mixedculture of cecal bacteria.
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Sakata, T., Kojima, T., Fujieda, M. et al. Probiotic Preparations Dose-Dependently Increase Net Production Rates of Organic Acids and Decrease that of Ammonia by Pig Cecal Bacteria in Batch Culture. Dig Dis Sci 44, 1485–1493 (1999). https://doi.org/10.1023/A:1026624423767
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DOI: https://doi.org/10.1023/A:1026624423767