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Wegener's granulomatosis diagnosed by testicular biopsy

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Abstract

Urogenital involvement, other than the kidneys,is extremely rare in Wegener'sgranulomatosis (WG) and occurs in less than 1%of the cases. When encountered it isconfined to prostate, bladder, urethra, cervix,and vagina. Granulomatous infiltration ofthe testis from WG has not been cited in themedical literature. We report a case of WGin a Hispanic male who presented withsensorineural hearing loss and hemoptysis. Hehad a pulmonary lesion and a painless righttesticular mass, which was found to havenecrotizing granulomas on excisional biopsy.This may be the first reported case of WGdiagnosed by testicular biopsy as testicularinvolvement is rare in WG. We believe thatthe actual incidence of testicular involvementin WG may be higher as genitalexamination may be ignored during routinephysical examinations.

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Agraharkar, M., Gokhale, S. & Gupta, R. Wegener's granulomatosis diagnosed by testicular biopsy. Int Urol Nephrol 34, 559–564 (2002). https://doi.org/10.1023/A:1025642217482

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