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Screening for functional genes related to a novel gene, AngRem104, in human mesangial cells by cDNA microarray

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Abstract

AngRem104 is a novel gene recently identified in human mesangial cells induced by angiotensin II. cDNA microarray was performed to screen the functional genes related to AngRem104. Thirty-one genes were up-regulated while 2 genes were down-regulated. Of all the up-regulated genes, fibronectin, one of the major extracellular matrixes, was up-regulated with over-expression of AngRem104.

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Authors and Affiliations

  1. Renal Division of Peking University First Hospital, Institute of Nephrology, Peking University, Beijing, 100034, P.R. China

    Xiu-Bin Liang, Hong Zhang, An-Yu Zhou & Hai-Yan Wang

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  1. Xiu-Bin Liang
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  2. Hong Zhang
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  3. An-Yu Zhou
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  4. Hai-Yan Wang
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Correspondence to Hong Zhang.

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Liang, XB., Zhang, H., Zhou, AY. et al. Screening for functional genes related to a novel gene, AngRem104, in human mesangial cells by cDNA microarray. Biotechnology Letters 25, 139–142 (2003). https://doi.org/10.1023/A:1021967302249

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  • DOI: https://doi.org/10.1023/A:1021967302249

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