Abstract
The post-ingestion bioavailability of arsenic (As) in alluvial soil and mineral beneficiation waste from Ron Phibun, Nakhon Si Thammarat Province, Thailand has been investigated using a physiologically-based extraction test (PBET). The method utilises synthetic leaching fluids closely analogous to those of the human stomach and small intestine, upon which the leaching duration and ambient temperature of the experimental procedure are also directly based. Replicate analyses of Ron Phibun alluvium samples holding 1406 and 2123 μg As g-1 respectively indicated an average stomach absorption of 11.2% (of total soil As). Gross absorption increased to 18.9% following translocation through a simulated small-intenstine regime. Higher gross absorption (35.7%) was recorded during PBET analysis of a flotation waste sample holding c. 2% total As. Within- and between-site variations of As bioavailability can principally be ascribed to mineralogical factors, notably the relative abundances of sulphide, arsenide, arsenate and oxide hosts within the soil/flotation waste matrix. The PBET provides a potentially valuable mechanism for refining risk assessments of sites subject to natural or anthropogenic As contamination. Through the substitution of total soil As values with input data which relate specifically to bioavailable As, risk calculations derived using established models such as the US-EPA package Risk Assistant may prove more realistic, thus facilitating improved cost-benefit analysis of site remediation options. Assessment of the relative human risks associated with potable water consumption and contaminated soil ingestion at Ron Phibun has signified that the latter could constitute a more significant As exposure pathway than recognised previously. Further evaluation of the precise soil ingestion levels of inhabitants residing on the As-rich alluvium which covers much of the district is, therefore, warranted.
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References
Abernathy, C. O. 1993. Draft drinking water criteria document on arsenic. US-EPA Science Advisory Board report. Contract 68–C8–0033, Washington, USA.
Borgono J. M., Venturino, H. and Vicent, P. 1980. Clinical and epidemiological study of arsenism in northern Chile. Reviews in Medicine, Chile, 108, 1039–1048.
Breward, N. and Peachey, D. 1983. The development of a rapid scheme for the elucidation of the chemical speciation of elements in sediments. Science of the Total Environment, 29, 155–162.
Cebrian, M. E. Albores, A. Aquilar, M. and Blakely, E. 1983. Chronic arsenic poisoning in the north of Mexico. Human Toxicology, 2, 121–133.
Chakraborty, A. K. and Saha, K. C. 1987. Arsenical dermatosis from tubewell water in west Bengal. Indian Journal of Medical Research, 85, 326–334.
Chen, S. L., Dzeng, S. R. and Yang, M. H. 1994. Arsenic species in the Blackfoot disease area, Taiwan. Environmental Science and Technology, 28, 877–881.
Davis, A., Drexler, J. W., Ruby, M. V. and Nicholson, A. 1993. Micromineralogy of mine wastes in relation to lead bioavailability, Butte, Montana. Environmental Science and Technology, 27, 1415–1424.
Ferguson, C. C. and Denner, J. M. 1995. UK Action (or intervention) values for contaminants in soil for protection of human health. Proceedings of the Fifth International FZK/TNO Conference on Contaminated Soil 1995. Maastricht, Netherlands, 2, 1199–1200.
Fergusson, J. E. 1990. The Heavy Elements: Chemistry, Environmental Impact and Health Effects. Pergamon Press, Oxford, UK, 614 pp.
Fordyce, F. M., Williams, T. M, Paijitprapapon, A. and Charoenchaisri, P. 1994. Hydrogeochemistry of arsenic in Ron Phibun District, Sakhon Si Thammarat Province, Thailand. British Geological Survey Overseas Geology Series Technical Report WC/94/79/R.
Freeman, G. B., Johnson, J. D., Killinger, J. M., Laio, S. C., Davis, A. O., Ruby, M. V., Chaney, R. L., Lovre, S. C. and Bergstrom, P. D. 1993. Bioavailability of arsenic in soil impacted by smelter activities following oral administration in rabbits. Fundamental and Applied Toxicology, 20, 1–11.
Goldsborough, D. G. and Smit, P. J. 1995. RISC: computer models for soil investigation, risk analysis and urgency estimation. Proceedings, Fifth International FZK/TNO Conference on Contaminated Soil 95 (Maastricht, The Netherlands), 1, 581–588.
Hampshire Research Institute. 1996. RISK ASSISTANT for Windows. 9426 Forest Haven Drive, Alexandria, Virginia 22309–3151, USA.
HEAST 1996. Heath Effects Assessment Summary Tables for Arsenic and its Compounds, USEPA, November 1996 Update.
Hopenhayn-Rich, C., Biggs, M. L., Fuchs, A., Bergoglio, R., Tello, E. E., Nicolli, H. and Smith, A. H. 1996. Bladder cancer mortality associated with arsenic in drinking water in Argentina. Epidemiology, 7 no. 2, 117–124.
Kimborough, R. D., Falk, H., Stehr, P. and Fries, G. 1984. Health implications of 2,3,7,8-tetrachlorodibenzo-pdioxin (TCDD) contamination of residential soil. Journal Toxicology and Environmental Health, 14, 47–93.
Ruby, M. V., Davis, A., Schoof, R, Eberle, S. and Sellstone, C. M. 1996. Estimation of lead and arsenic bioavailability using a physiologically based extraction test. Environmental Science and Technology, 30, 422–430.
Stanek, E. J. and Calabrese, E. J. 1995. Daily Estimates of Soil Ingestion in Children. Environmental Health Perspectives, 103, no 3, 276–285.
Tessier, A., P. G. C. Campbell and M. Bisson. 1979. Sequential extraction procedure for the speciation of particulate trace metals. Analytical Chemistry, 51, 844–851.
Theelen, R. M. C. and Nijhof, A. G. 1995. Risk assessment of lead in soil; an alternative approach to calculate maximum tolerable levels. Proceedings of the Fifth International FZK/TNO Conference on Contaminated Soil 1995, Maastricht, Netherlands, 1, 557–564.
Torre, M and Rodriquez, A. R. 1991. Effect of Dietary fibre and phytic acid on mineral bioavailability. Critical Reviews in Food Science and Nutrition, 39, 1–22.
Tsuji, J. S. 1993. Effects of chemical and physical form on the bioavailability of arsenic in the environment. Proceedings of the First International Conference on Arsenic and Health, New Orleans, July, 1993.
US-EPA. 1989. Exposure Factors Handbook EPA/600/8- 89/043 Office of Health and Environmental Assessment Washington DC.
Williams, T. M. 1992. Trace metal speciation in surficial sediments from Loch Dee, south-west Scotland, U.K. Environmental Geology, 21, 62–70.
Williams, T. M., Fordyce, F. M. Paijitprapapon, A. and Charoenchaisri, P. 1996. Arsenic contamination in surface drainage and groundwater in part of the South-east Asia tin belt, Nakhon si Thammarat Province, Southern Thailand. Environmental Geology, 27, 16–33.
Williams, T. M. and Breward, N. 1995. Environmental impacts of gold and complex sulphide mining with particular reference to arsenic contamination. British Geological Survey Overseas Geology Series Technical Report WC/95/2.
Wong, M., Bundy, D. and Golden M. 1988. Quantitative assessment of geophageous behaviour as a potential source of exposure to geohelminth infection. Transactions of the Royal Society for Tropical Medicine and hygiene, 82, 621–625.
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Williams, T., Rawlins, B., Smith, B. et al. In-Vitro Determination of Arsenic Bioavailability in Contaminated Soil and Mineral Beneficiation Waste from Ron Phibun, Southern Thailand: A Basis for Improved Human Risk Assessment. Environmental Geochemistry and Health 20, 169–177 (1998). https://doi.org/10.1023/A:1006545817478
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DOI: https://doi.org/10.1023/A:1006545817478