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Production of poly-γ-glutamic acid by fed-batch culture of Bacillus licheniformis

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Abstract

Fed-batch cultures of Bacillus licheniformis produced poly-γ-glutamic acid (PGA), a water-soluble biodegradable polymer. PGA reached 35 g l−1 with a productivity of 1 g l−1 h−1 by pulsed-feeding of citric acid (1.44 g h−1) and l-glutamic acid (2.4 g h−1) when citric acid was depleted from the culture medium.

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Authors and Affiliations

  1. Department of Chemical Engineering and BioProcess Engineering Research Center, Korea Advanced Institute of Science and Technology, 373-1 Kusong-dong, Yusong-gu, Taejon, 305-701, Korea

    Sung Ho Yoon, Jin Hwan Do, Sang Yup Lee, Ho Nam Chang & Ho Nam Chang

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  1. Sung Ho Yoon
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  2. Jin Hwan Do
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  3. Sang Yup Lee
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  4. Ho Nam Chang
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Yoon, S.H., Hwan Do, J., Yup Lee, S. et al. Production of poly-γ-glutamic acid by fed-batch culture of Bacillus licheniformis. Biotechnology Letters 22, 585–588 (2000). https://doi.org/10.1023/A:1005625026623

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  • DOI: https://doi.org/10.1023/A:1005625026623

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