Abstract
Pd(II) complexes with glutamic acid of the composition K[Pd(HGlu)Cl2] (I) and [Pd(HGlu)2] (II) were synthesized and studied by IR and electronic absorption spectroscopy methods. Pd2+–H2O–Cl– and Pd2+–H2O–Cl––H2Glu systems were analyzed by pH-metric titration. The most essential Pd(II) complex forms were established by mathematical modeling and their formation constants were calculated. The electronic absorption spectra of complexes I and II were measured in aqueous and physiological solutions. Complex I was found to be biologically active and to exhibit antimetastatic properties.
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REFERENCES
Rosenberg, B., Platinum Metals Rev., 1971, vol. 15, p. 42.
Cleare, M.Y., Hoeyche, Y.D., and Mc Auliffe, C.F., Proc.XVIth Int. Conf. on Coordination Chemistry, Dublin , 1974.
Thomson, A.J., Williams, R.M., and Reslova, S., Structure and Bonding, 1972, vol. 11, p. 1.
Drobnicky, M., Krekulova, A., and Kubelkova, H., Foliamicrob, 1971, vol. 16, p. 548.
Weloch, C.W., J. Nat. Cancer. Inst., 1971, vol. 47, p. 1071.
Zakharova, I.A., Moshkovskii, Yu.S., Suraikina, T.I., and Fonshtein, L.M., Dokl. Akad. Nauk SSSR, 1975, vol. 222, no. 5, p. 1229.
Zakharova, I.A., Moshkovskii, Yu.S., Suraikina, T.I., and Fonshtein, L.M., Koord. Khim., 1976, vol. 2, no. 12, p. 1642.
Chakrawarti, P.B., J. Sci. Ind. Res., 1989, vol. 48, no. 11, p. 529.
Campbell, K., 2002/11/22, http://www.miningweekly.co.za/min/news/today/show = 29712.
Efimenko, I.A., Kurbakova, A.P., Ivanova, N.A., et al., RF Patent 2022968, Byull. Izobret., 1994, no 21.
Efimenko, I.A., Lokshin, B.V., Ivanova, N.A., et al., RF Patent 2089186, Byull. Izobret., 1997, no. 25.
Efimenko, I.A., Koord. Khim., 1998, vol. 24, no. 4, p. 282.
Efimenko, I.A., Morozov, I.S., Ivanova, I.A., and Ivanova, N.A., RF Patent 2138258, Byull. Izobret., 1999, no. 27.
Yatsimirskii, K.B., Mosin, V.V., Kozachkova, A.N., and Efimenko, I.A., Koord. Khim., 1993, vol. 19, no. 10, p. 793.
Yatsimirskii, K.B. and Berezin, I.V., Izv. Akad. Nauk USSR, 1976, no. 7, p. 1490.
Biryukov, A.A. and Shlenskaya, V.I., Zh. Neorg. Khim., 1964, vol. 9, no. 4, p. 813.
Droll, H.A., Block, B.P., and Fernelius, W.C., J. Phys. Chem., 1957, vol. 61, no. 4, p. 1000.
Stability Constants Database SCQUERY, 1993, IUPAC and Academie Software SCQUERY, Version 1.38.
Buslaeva, T.M., Umreiko, D.S., and Novitskii, G.G., Khimiya i spektroskopiya galogenidov platinovykh metallov(Chemistry and Spectroscopy of Platinum Metal Halides), Minsk: Universitetskoe, 1990, p. 279.
Elding, L.J. and Olsson, L.F., J. Phys Chem, 1978, vol. 82, no. 1, p. 69.
Burger, K., Biocoordination Chemistry, 1990, Szeged: Ellis Horwood Series in Inorganic Chemistry.
Sintez kompleksnykh soedinenii metallov platinovoi gruppy, Spravochnik(Synthesis of Complex Compounds of Platinum Group Metals, a Handbook), Chernyaev, I.I., Ed., Moscow: Nauka, 1964, p. 340.
Evseev, A.M. and Nikolaeva, L.S., Matematicheskoe modelirovanie khimicheskikh ravnovesii(Mathematical Simulation of Chemical Equilibria), Moscow: Mos. Gos.Univ., 1988, p. 192.
Nabivanets, B.V. and Kalabina, L.V., Zh. Neorg. Khim., 1970, vol. 15, no. 6, p. 1595.
Izatt, R.M., Eatough, D., and Christensen, J.J., J. Chem.Soc., Sect. A, 1967, no. 8, p. 1301.
Yatsimirskii, K.B. and Kozachkova, A.N., Dokl. Akad. Nauk USSR, Ser. B ,1989, no. 11, p. 57.
Maiorova, I.V., Dobrynina, N.A., Nikolaeva, L.S., and Evseev, A.M., Koord. Khim., 1993, vol. 19, no. 1, p. 74.
Vagg, R.S., Acta Crystallogr., Sect. B: Struct. Crystallogr. Cryst. Chem., 1979, vol. 35, no. 2, p. 341.
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Akat'eva, M.E., Erofeeva, O.S., Dobrynina, N.A. et al. Interaction of Pd(II) with Glutamic Acid. Russian Journal of Coordination Chemistry 30, 584–590 (2004). https://doi.org/10.1023/B:RUCO.0000037439.30356.e0
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DOI: https://doi.org/10.1023/B:RUCO.0000037439.30356.e0