Abstract
Sertoli cell proliferation occurs mainly during the phase of rapid spermatogonial proliferation, allowing the cyst-forming Sertoli cells to form an increasingly large space for housing the growing germ cell clone. There is no information in fish on the regulation of Sertoli cell proliferation; follicle-stimulating hormone (FSH) stimulates Sertoli cell proliferation in mammals. Increasing or decreasing FSH and FSH receptor expression experimentally in male African catfish was associated with respective changes in Sertoli cell proliferation or testis growth, suggesting that also in fish, one role of FSH may be to regulate Sertoli cell numbers.
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Schulz, R., van Dijk, W. & Bogerd, J. Sertoli cell proliferation and FSH signalling in African catfish, Clarias gariepinus . Fish Physiology and Biochemistry 28, 223–224 (2003). https://doi.org/10.1023/B:FISH.0000030537.56120.fe
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DOI: https://doi.org/10.1023/B:FISH.0000030537.56120.fe