Skip to main content
Log in

Assessing Depressive Symptoms in Multiple Sclerosis: Is It Necessary to Omit Items from the Original Beck Depression Inventory?

  • Published:
Journal of Behavioral Medicine Aims and scope Submit manuscript

Abstract

Overlap between depression scale item content and medical symptoms may exaggerate depression estimates for patients with multiple sclerosis (MS). We reconsider Mohr and co-workers' (1997) recommendation to omit Beck Depression Inventory (BDI) items assessing work ability (item 15), fatigue (17), and health concerns (20) for MS patients. Subjects were medical patients with either MS (n = 105) or a medical disorder for which the BDI is empirically supported [diabetes mellitus (DM), n = 71; chronic pain (CP), n = 80], psychiatric patients with depressive disorder (MDD; n = 37), and healthy controls (HC; n = 80). Relative scores for the eight “somatic” BDI items were analyzed by multivariate analysis of variance with demographic variables and BDI total as covariates. The only significant difference was MS > HC (item 15). On raw scores, MS patients exceeded HCs on items 15 and 21 (sexual disinterest), but this was attributable to the low HC item endorsement. There were no other differences on somatic items or item-total correlations. Scale consistency was good across groups, regardless of item omission. Somatic items were unassociated with major MS parameters. We thus encourage continued application of the full BDI for assessing depressive symptoms in patients with MS.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

REFERENCES

  • American Psychiatric Association (1994). Diagnostic and Statistical Manual of Mental Disorders: Fourth Edition, American Psychiatric Association, Washington, DC.

    Google Scholar 

  • Anastasi, A. (1988). Psychological Testing, 6th ed., Macmillan, New York.

    Google Scholar 

  • Beck, A. T., and Steer, R. A., (1987). Manual for the Revised Beck Depression Inventory, Psychological Corporation, San Antonio, TX.

    Google Scholar 

  • Beck, A. T., Steer, R. A., and Garbin, M. G. (1988). Psychometric properties of the Beck Depression Inventory: Twenty-five years of evaluation. Clin. Psychol. Rev. 8: 77-100.

    Google Scholar 

  • Beck, A. T., Steer, R. A., and Brown, G. K. (1996). The Beck Depression Inventory—II, Psychological Corporation, San Antonio, TX.

    Google Scholar 

  • Cavanaugh, S., Clark, D. C., and Gibbons, R. D. (1983). Diagnosing depression in the hospitalized medically ill. Psychosomatics 24: 809-815.

    Google Scholar 

  • Clark, D. C., Cavanaugh, S. V., and Gibbons, R. D. (1983). The core symptoms of depression in medical and psychiatric patients. J. Nerv. Ment. Dis. 173: 482-487.

    Google Scholar 

  • Dobson, K. (1989). A meta-analysis of the efficacy of cognitive therapy for depression. J. Consult. Clin. Psychol. 57: 414-419.

    Google Scholar 

  • Fava, M., and Rosenbaum, J. (1995). Pharmacotherapy and somatic therapies. In Beckham E., and Leber, W. (eds.), Handbook of Depression, 2nd ed., Guilford Press, New York, pp. 280-301.

    Google Scholar 

  • Fawcett, J., Scheftner, W., Clark, D., Hedeker, D., Gibbons, R., and Coryell, W. (1987). Clinical predictors of suicide in patients with major affective disorders: A controlled prospective study. Am. J. Psychiatry 144: 35-40.

    Google Scholar 

  • First, M. B., Spitzer, R. L., Gibbon, M., and Williams, J. B. W. (1995). Structured Clinical Interview for the DSM-IV Axis I Disorders—Patient Edition (SCID I/ P, Version 2.0), Biometrics Research Department, New York.

    Google Scholar 

  • Fischer, J. S., Foley, F. W., Aikens, J. E., Ericson, G. D., Rao, S. M., and Schindell, S. S. (1994). What do we really know about cognitive dysfunction, affective disorders, and stress in multiple sclerosis? A practitioner's guide. J. Neurol. Rehab. 8: 151-64.

    Google Scholar 

  • Geisser, M. E., Roth, R. S., and Robinson, M. E. (1997). Assessing depression among persons with chronic pain using the Center for Epidemiological Studies—Depression Scale and the Beck Depression Inventory: A comparative analysis. Clin. J. Pain 13: 153-170.

    Google Scholar 

  • Isometsa, E. T., Aro, H. M., Henrikkson, M. M., Heikenen, M. E., and Lonnqvist, J. K. (1994). Suicide in major depression in different settings. J. Clin. Psychiatry 55: 523-527.

    Google Scholar 

  • Hill, A. B., Kemp-Wheeler, and Jones, S. A. (1987). Subclinical and clinical depression: Are analogue studies justifiable? Person. Indiv. Diff. 8: 113-120.

    Google Scholar 

  • Hollon, S., Shelton, R., and Davis, D. (1993). Cognitive therapy for depression: Conceptual issues and clinical efficacy. J. Consult. Clin. Psychol. 61: 270-275.

    Google Scholar 

  • Huber, S. J., Rammohan, K. W., Bornstein, R. A., and Christy, J. A. (1993). Depressive symptoms are not influenced by severity of multiple sclerosis. Neuropsychiatry Neuropsychol. Behav. Neurol. 6: 177-180.

    Google Scholar 

  • IFNB Multiple Sclerosis Study Group and the University of British Columbia MS/MRI Analysis Group (1995). Interferon beta-1b in the treatment of multiple sclerosis: Final outcome of the randomized controlled trial. Neurology 45: 1277-1285.

    Google Scholar 

  • Jacobs, L. D., Cookfair, D. L., Rudick, R. A., Herndon, R. M., Richert, J. R., Salazar, A. M., Fischer, J. S., Goodkin, D. E., Granger, C. V., Simon, J. H., Alam, J. J., Bartoszak, D. M., Bourdette, D. N., Braiman, J., Brownscheidle, C. M., Coats, M. E., Cohan, S. L., Dougherty, D. S., Kinkel, R. P., Mass, M. K., Munschauer, F. E., 3rd, Priore, R. L., Pullicino, P. M., Scherokman, B. J., and Whitham, R. H. (1996). Intramuscular interferon beta-1a for disease progression in relapsing multiple sclerosis. The Multiple Sclerosis Collaborative Research Group (MSCRG). Ann. Neurol. 39: 285-294.

    Google Scholar 

  • Joffe, R. T., Lippert, G. P., Gray, T. A., Sawa, G., and Horvath, Z. (1987). Mood disturbance and multiple sclerosis. Arch. Neurol. 44: 376-378.

    Google Scholar 

  • Johnson, K. P., Brooks, B. R., Cohen, J. A., Ford, C. C., Goldstein, J., Lisak, R. P., Myers, L. W., Panitch, H. S., Rose, J. W., Schiffer, R. B., Vollmer, T., Weiner, L. P., Wolinsky, J. S., and the Copolymer 1 Multiple Sclerosis Study Group (1995). Copolymer 1 reduces relapse rate and improves disability in relapsing-remitting multiple sclerosis: Results of a phase III multicenter, double-blind, placebo-controlled study. Neurology 45: 1268-1276.

    Google Scholar 

  • Johnson, S. K., DeLuca, J., and Natelson, B. H. (1996). Depression in fatiguing illness: comparing patients with chronic fatigue syndrome, multiple sclerosis and depression. J. Affect. Dis. 39: 21-30.

    Google Scholar 

  • Klerman, G. (1987). Clinical epidemiology of suicide. J. Clin. Psychiatry 48: 33-38.

    Google Scholar 

  • Kurtzke, J. F. (1983). Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS). Neurology 33: 1444-1452.

    Google Scholar 

  • Lapp, W. M., and Collins, R. L. (1993). Relative/proportional scoring of the Ways of Coping Checklist: Is it advantageous or artifactual? Multivar. Behav. Res. 28: 483-512.

    Google Scholar 

  • Lustman, P. J., Freedland, K. E., Carney, R. M., Hong, B. A., and Clouse, R. E. (1992). Similarity of depression in diabetic and psychiatric patients. Psychosom. Med. 54: 602-611.

    Google Scholar 

  • Lustman, P. J., Clouse, R. E., Griffith, L. S., Carney, R. M., and K. E. Freedland, (1997). Screening for depression in diabetes using the Beck Depression Inventory. Psychosom. Med. 59(1): 24-31.

    Google Scholar 

  • Mackenzie, T., and Popkin, M. (1990). Medical illness and suicide. In Blumenthal, S., and Kupfer, D. (eds.), Suicide Over the Life Cycle: Risk Factors, Assessment and Treatment of Suicidal Patients, American Psychiatric Press, Washington, DC, pp. 205-234.

    Google Scholar 

  • Maguire, P., Hopwood, P., Tarrier, N., and Howell, T. (1985). Treatment of depression in cancer patients. Acta Psychiatr. Scand. 72 (Suppl. 320): 81-84.

    Google Scholar 

  • Mohr, D. C., Goodkin, D. E., Likosky, W., Beutler, L., Gatto, N., and Langan, M. K. (1997). Identification of Beck Depression Inventory items related to multiple sclerosis. J. Behav. Med. 20: 407-414.

    Google Scholar 

  • Moorey, S., and Greer, S. (1989). Adjuvant psychological therapy: A cognitive-behavioural therapy for patients with cancer. Behav. Psychother. 17: 177-190.

    Google Scholar 

  • Novy, D. M., Nelson, D. V., Berry, L. A., and Averill, P. M. (1995). What does the Beck Depression Inventory measure in chronic pain? A reappraisal. Pain 61: 261-270.

    Google Scholar 

  • Pokorny, A. (1964). Suicide rates in various psychiatric disorders. J. Nerv. Ment. Dis. 139: 499-506.

    Google Scholar 

  • Poser, C. M., Paty, D. W., Scheinberg, L., McDonald, W. I., Davis, F. A., Ebers, G. C., Johnson, K. P., Sibley, S. A., Silberberg, D. H., and Tourtellotte, W. W. (1983). New diagnostic criteria for multiple sclerosis. Ann. Neurol. 13: 227-231.

    Google Scholar 

  • Rao, S. M. (1986). Neuropsychology of multiple sclerosis: A critical review. J. Clin. Exp. Neuropsychol. 8: 503-542.

    Google Scholar 

  • Robins, L. N., Helzer, J. E., Croughan, J., and Ratcliff, K. S. (1981). National Institute of Mental Health Diagnostic Interview Schedule: Its history, characteristics, and validity. Arch. Gen. Psychiatry 38: 381-389.

    Google Scholar 

  • Reck, J. R., Smith, T. W., Ward, J. R., and Milano, R. (1989). Disability and depression in rheumatoid arthritis: A multi-trait, multimethod investigation. Arth. Rheum. 32: 1100-1106.

    Google Scholar 

  • Rudick, R., Goodkin, D., and Ransohoff, R. (1992). Pharmacotherapy of multiple sclerosis: Current status. Cleveland Clin. J. Med. 59: 267-277.

    Google Scholar 

  • Rudick, R. A., Medendorp, S. V., Namey, M., Boyle, S., and Fischer, J. (1995). Multiple sclerosis progression in a natural history study: Predictive value of cerebrospinal fluid free kappa light chains. Multiple Sclerosis 1: 150-155.

    Google Scholar 

  • Schiffer, R. (1987). The spectrum of depression in multiple sclerosis: An approach for clinical management. Arch. Neurol. 44: 596-599.

    Google Scholar 

  • Sibley, W. A. (1990). The diagnosis and course of multiple sclerosis. In Rao, S. M. (ed.), Neurobehavioral Aspects of Multiple Sclerosis, Oxford University Press, New York, pp. 5-14.

    Google Scholar 

  • Stenager, E. N., Stenager, E., Koch-Henriksen, N., et al. (1992). Suicide and multiple sclerosis: An epidemiological investigation. J. Neurol. Neurosurg. Psychiatry 55: 542-545.

    Google Scholar 

  • Sullivan, M. J., Weinshenker, B., Mikail, S., and Bishop, S. R. (1995). Screening for major depression in the early stages of multiple sclerosis. Can. J. Neurol. Sci. 22: 228-231.

    Google Scholar 

  • Vercoulen, J. H., Hommes, O. R., Swanink, C. M., Jongen, P. J., Fennis, J. F., Galama, J. M., van der Meer, J. W., and Bleijenberg G. (1996). The measurement of fatigue in patients with multiple sclerosis. A multidimensional comparison with patients with chronic fatigue syndrome and healthy subjects. Arch. Neurol. 53: 642-649.

    Google Scholar 

  • Weich, S. (1997). Prevention of the common mental disorders: A public health perspective. Psychol. Med. 27: 757-764.

    Google Scholar 

  • Whitlock, F. (1986). Suicide and physical illness. In Roy, A. (ed.), Suicide, Williams & Wilkins, Baltimore.

    Google Scholar 

  • Williams, A. C., and Richardson, P. H. (1993). What does the BDI measure in chronic pain? Pain 55: 259-266.

    Google Scholar 

Download references

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Aikens, J.E., Reinecke, M.A., Pliskin, N.H. et al. Assessing Depressive Symptoms in Multiple Sclerosis: Is It Necessary to Omit Items from the Original Beck Depression Inventory?. J Behav Med 22, 127–142 (1999). https://doi.org/10.1023/A:1018731415172

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/A:1018731415172

Navigation