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Kinetic-Effect Models and Their Applications

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Abstract

This article focuses on mathematical models that analyze the time course of drug effects in humans. Any such model, whether parametric or nonparametric, is termed a kinetic-effect model (KEM). These models serve to describe (interpolation) and to predict (extrapolation) the effect–time profile. KEMs are applicable to many problems in pharmaceutics, pharmacology, and clinical pharmacology.

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Authors and Affiliations

  1. Department of Pharmacology and Division of Immunology and Organ Transplantation Department of Surgery, The University of Texas Medical School, 6431 Fannin Street, MSMB6.252, Houston, Texas, 77030

    Joachim Grevel

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  1. Joachim Grevel
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Grevel, J. Kinetic-Effect Models and Their Applications. Pharm Res 4, 86–91 (1987). https://doi.org/10.1023/A:1016402616081

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